Alpha 2.0
Login Register
» Authors » Michael Quasney

Michael Quasney

Explore the profile of Michael Quasney including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 42
Citations 974
Followers 0
Related Specialties
Critical Care
Pediatrics
Emergency Medicine
Top 10 Co-Authors
Neal J Thomas
Natalie Z Cvijanovich
Jeffrey Nowak
Michael T Bigham
Scott L Weiss
Geoffrey L Allen
Hector R Wong
Julie C Fitzgerald
Keith Meyer
Nick Anas
Published In
Crit Care Med
Crit Care
Pediatr Crit Care Med
Am J Respir Crit Care Med
Res Sq
Affiliations
Soon will be listed here.
Recent Articles
1.
Identification and transcriptomic assessment of latent profile pediatric septic shock phenotypes
Atreya M, Huang M, Moore A, Zheng H, Hasin-Brumshtein Y, Fitzgerald J, et al.
Crit Care . 2024 Jul; 28(1):246. PMID: 39014377
Background: Sepsis poses a grave threat, especially among children, but treatments are limited owing to heterogeneity among patients. We sought to test the clinical and biological relevance of pediatric septic...
2.
Revisiting Post-ICU Admission Fluid Balance Across Pediatric Sepsis Mortality Risk Strata: A Secondary Analysis of a Prospective Observational Cohort Study
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Crit Care Explor . 2024 Jan; 6(1):e1027. PMID: 38234587
Objectives: Post-ICU admission cumulative positive fluid balance (PFB) is associated with increased mortality among critically ill patients. We sought to test whether this risk varied across biomarker-based risk strata upon...
3.
Derivation, validation, and transcriptomic assessment of pediatric septic shock phenotypes identified through latent profile analyses: Results from a prospective multi-center observational cohort
Atreya M, Huang M, Moore A, Zheng H, Hasin-Brumshtein Y, Fitzgerald J, et al.
Res Sq . 2023 Dec; PMID: 38105983
Background: Sepsis poses a grave threat, especially among children, but treatments are limited due to clinical and biological heterogeneity among patients. Thus, there is an urgent need for precise subclassification...
4.
SERUM SOLUBLE ENDOGLIN IN PEDIATRIC SEPTIC SHOCK-ASSOCIATED MULTIPLE ORGAN DYSFUNCTION SYNDROME
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Shock . 2023 Jul; 60(3):379-384. PMID: 37493567
Background: Endothelial activation is a key driver of multiple organ dysfunction syndrome (MODS). Soluble endoglin (sENG) is expressed by mature and progenitor endothelial cells and thought to have angiogenic properties....
5.
Revisiting post-ICU admission fluid balance across pediatric sepsis mortality risk strata: A secondary analyses from a prospective observational cohort study
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Res Sq . 2023 Jul; PMID: 37461591
Introduction: Post-ICU admission cumulative positive fluid balance (PFB) is associated with increased mortality among critically ill patients. We sought to test whether this risk varied across biomarker-based risk strata upon...
6.
Prognostic and predictive value of endothelial dysfunction biomarkers in sepsis-associated acute kidney injury: risk-stratified analysis from a prospective observational cohort of pediatric septic shock
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Crit Care . 2023 Jul; 27(1):260. PMID: 37400882
Background: Sepsis-associated acute kidney injury (SA-AKI) is associated with high morbidity, with no current therapies available beyond continuous renal replacement therapy (CRRT). Systemic inflammation and endothelial dysfunction are key drivers...
7.
Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Crit Care . 2023 Jun; 27(1):250. PMID: 37365661
Background: Sepsis is associated with significant mortality. Yet, there are no efficacious therapies beyond antibiotics. PCSK9 loss-of-function (LOF) and inhibition, through enhanced low-density lipoprotein receptor (LDLR) mediated endotoxin clearance, holds...
8.
A Targeted Analysis of Serial Cytokine Measures and Nonpulmonary Organ System Failure in Children With Acute Respiratory Failure: Individual Measures and Trajectories Over Time
Ardila S, Weeks H, Dahmer M, Kaciroti N, Quasney M, Sapru A, et al.
Pediatr Crit Care Med . 2023 May; 24(9):727-737. PMID: 37195096
Objectives: There is a need for research exploring the temporal trends of nonpulmonary organ dysfunction (NPOD) and biomarkers in order to identify unique predictive or prognostic phenotypes. We examined the...
9.
Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Res Sq . 2023 Feb; PMID: 36778250
Sepsis is associated with significant mortality, yet there are no efficacious therapies beyond antibiotics and supportive care. In adult sepsis studies, PCSK9 loss-of-function (LOF) and inhibition has shown therapeutic promise,...
10.
Integrated PERSEVERE and endothelial biomarker risk model predicts death and persistent MODS in pediatric septic shock: a secondary analysis of a prospective observational study
Atreya M, Cvijanovich N, Fitzgerald J, Weiss S, Bigham M, Jain P, et al.
Crit Care . 2022 Jul; 26(1):210. PMID: 35818064
Background: Multiple organ dysfunction syndrome (MODS) is a critical driver of sepsis morbidity and mortality in children. Early identification of those at risk of death and persistent organ dysfunctions is...