Geoffrey A Mueller
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Explore the profile of Geoffrey A Mueller including associated specialties, affiliations and a list of published articles.
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95
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1460
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Recent Articles
11.
Degtyareva N, Placentra V, Gabel S, Klimczak L, Gordenin D, Wagner B, et al.
Nucleic Acids Res
. 2023 Apr;
51(10):5056-5072.
PMID: 37078607
Mutational signatures discerned in cancer genomes, in aging tissues and in cells exposed to toxic agents, reflect complex processes underlying transformation of cells from normal to dysfunctional. Due to its...
12.
Min J, Foo A, Gabel S, Perera L, DeRose E, Pomes A, et al.
Front Allergy
. 2023 Mar;
4:1133412.
PMID: 36960093
Introduction: Pet lipocalins are respiratory allergens with a central hydrophobic ligand-binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to influence allergenicity, but little is...
13.
Foo A, Nesbit J, Gipson S, DeRose E, Cheng H, Hurlburt B, et al.
J Agric Food Chem
. 2023 Feb;
71(6):2990-2998.
PMID: 36728846
Peanut and tree-nut allergies are frequently comorbid for reasons not completely understood. Vicilin-buried peptides (VBPs) are an emerging family of food allergens whose conserved structural fold could mediate peanut/tree-nut co-allergy....
14.
LaHood N, Min J, Keswani T, Richardson C, Amoako K, Zhou J, et al.
J Clin Invest
. 2023 Jan;
133(2).
PMID: 36647835
In IgE-mediated food allergies, exposure to the allergen activates systemic allergic responses. Oral immunotherapy (OIT) treats food allergies through incremental increases in oral allergen exposure. However, OIT only induces sustained...
15.
Klemm B, Singh D, Smith C, Hsu A, Dillard L, Krahn J, et al.
Proc Natl Acad Sci U S A
. 2022 Sep;
119(37):e2123092119.
PMID: 36067314
Levels of the cellular dNTPs, the direct precursors for DNA synthesis, are important for DNA replication fidelity, cell cycle control, and resistance against viruses. encodes a dGTPase (2'-deoxyguanosine-5'-triphosphate [dGTP] triphosphohydrolase...
16.
Foo A, Lafont B, Mueller G
FEBS Lett
. 2022 Jul;
596(19):2555-2565.
PMID: 35891619
The mosquito protein AEG12 encompasses a large (~ 3800 Å ) hydrophobic cavity which binds and delivers unsaturated fatty acids into biological membranes, allowing it to lyse cells and neutralize...
17.
Khatri K, Richardson C, Glesner J, Kapingidza A, Mueller G, Zhang J, et al.
PNAS Nexus
. 2022 Jul;
1(3):pgac054.
PMID: 35799831
Immunoglobulin E (IgE) antibody is a critical effector molecule for adaptive allergen-induced immune responses, which affect up to 40% of the population worldwide. Allergens are usually innocuous molecules but induce...
18.
Fernandez-Quintero M, DeRose E, Gabel S, Mueller G, Liedl K
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628231
Variable domains of camelid antibodies (so-called nanobodies or VH) are the smallest antibody fragments that retain complete functionality and therapeutic potential. Understanding of the nanobody-binding interface has become a pre-requisite...
19.
Ferreira F, Mueller G, Gilles S, Wills-Karp M
Front Allergy
. 2022 Apr;
2:800929.
PMID: 35386983
No abstract available.
20.
Foo A, Mueller G
Front Allergy
. 2022 Apr;
2:769728.
PMID: 35386965
There have been many attempts to identify common biophysical properties which differentiate allergens from their non-immunogenic counterparts. This review will focus on recent studies which examine two such factors: abundance...