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Geoffrey A Mueller

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Articles 95
Citations 1460
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Recent Articles
1.
Wright Z, Butay K, Krahn J, Wilson I, Gabel S, DeRose E, et al.
Nat Commun . 2025 Jan; 16(1):391. PMID: 39755678
Coronaviruses evade detection by the host immune system with the help of the endoribonuclease Nsp15, which regulates levels of viral double stranded RNA by cleaving 3' of uridine (U). While...
2.
Foo A, Edin M, Lin W, Lih F, Gabel S, Uddin M, et al.
Biochemistry . 2024 Jun; 63(14):1730-1737. PMID: 38915291
The cockroach allergen Bla g 1 encloses an exceptionally large hydrophobic cavity, which allows it to bind and deliver unsaturated fatty acid ligands. Bla g 1-mediated delivery of naturally occurring...
3.
Ball A, Khatri K, Glesner J, Vailes L, Wunschmann S, Gabel S, et al.
J Allergy Clin Immunol . 2024 May; 154(2):447-457. PMID: 38697404
Background: Human IgE (hIgE) mAbs against major mite allergen Der p 2 developed using human hybridoma technology were used for IgE epitope mapping and analysis of epitopes associated with the...
4.
Keswani T, LaHood N, Marini-Rapoport O, Karmakar B, Andrieux L, Reese B, et al.
J Allergy Clin Immunol . 2024 Mar; 153(6):1611-1620.e7. PMID: 38460677
Background: Clinical efficacy of oral immunotherapy (OIT) has been associated with the induction of blocking antibodies, particularly those capable of disrupting IgE-allergen interactions. Previously, we identified mAbs to Ara h...
5.
Walitt B, Singh K, LaMunion S, Hallett M, Jacobson S, Chen K, et al.
Nat Commun . 2024 Feb; 15(1):907. PMID: 38383456
Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is unknown, and no disease-modifying treatments are available. We used rigorous...
6.
Marini-Rapoport O, Fernandez-Quintero M, Keswani T, Zong G, Shim J, Pedersen L, et al.
Clin Exp Immunol . 2024 Feb; 216(1):25-35. PMID: 38346116
In peanut allergy, Arachis hypogaea 2 (Ara h 2) and Arachis hypogaea 6 (Ara h 6) are two clinically relevant peanut allergens with known structural and sequence homology and demonstrated...
7.
Pomes A, Smith S, Chruszcz M, Mueller G, Brackett N, Chapman M
J Allergy Clin Immunol . 2024 Jan; 153(3):560-571. PMID: 38181840
The allergen-IgE interaction is essential for the genesis of allergic responses, yet investigation of the molecular basis of these interactions is in its infancy. Precision engineering has unveiled the molecular...
8.
Min J, Keswani T, LaHood N, Lytle I, Marini-Rapoport O, Andrieux L, et al.
Clin Exp Allergy . 2024 Jan; 54(1):46-55. PMID: 38168500
Introduction: Adverse reactions are relatively common during peanut oral immunotherapy. To reduce the risk to the patient, some researchers have proposed modifying the allergen to reduce IgE reactivity, creating a...
9.
Quiroz-Delfi G, Rider C, Ferguson S, Jarmusch A, Mueller G
Anal Bioanal Chem . 2023 Nov; 416(1):175-189. PMID: 37910202
Consumers have unprecedented access to botanical dietary supplements through online retailers, making it difficult to ensure product quality and authenticity. Therefore, methods to survey and compare chemical compositions across botanical...
10.
Warden M, DeRose E, Tamayo J, Mueller G, Gavis E, Hall T
Nucleic Acids Res . 2023 Jul; 51(16):8836-8849. PMID: 37427795
The Drosophila melanogaster protein Glorund (Glo) represses nanos (nos) translation and uses its quasi-RNA recognition motifs (qRRMs) to recognize both G-tract and structured UA-rich motifs within the nos translational control...