Geoff Macintyre
Overview
Explore the profile of Geoff Macintyre including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
2066
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Recent Articles
1.
Hehir-Kwa J, Macintyre G
Science
. 2025 Jan;
387(6729):26-27.
PMID: 39745981
Germline structural variants are a risk factor for pediatric extracranial solid tumors.
2.
Schneider M, Cullen A, Pangonyte J, Skelton J, Major H, Van Oudenhove E, et al.
Genome Biol
. 2024 Mar;
25(1):62.
PMID: 38438920
Cancer cells often exhibit DNA copy number aberrations and can vary widely in their ploidy. Correct estimation of the ploidy of single-cell genomes is paramount for downstream analysis. Based only...
3.
Smith P, Bradley T, Morrill Gavarro L, Goranova T, Ennis D, Mirza H, et al.
Nat Commun
. 2023 Sep;
14(1):5992.
PMID: 37752102
No abstract available.
4.
Smith P, Bradley T, Morrill Gavarro L, Goranova T, Ennis D, Mirza H, et al.
Nat Commun
. 2023 Jul;
14(1):4387.
PMID: 37474499
The drivers of recurrence and resistance in ovarian high grade serous carcinoma remain unclear. We investigate the acquisition of resistance by collecting tumour biopsies from a cohort of 276 women...
5.
Vias M, Morrill Gavarro L, Sauer C, Sanders D, Piskorz A, Couturier D, et al.
Elife
. 2023 May;
12.
PMID: 37166279
High-grade serous ovarian carcinoma (HGSOC) is the most genomically complex cancer, characterized by ubiquitous mutation, profound chromosomal instability, and heterogeneity. The mutational processes driving chromosomal instability in HGSOC can be...
6.
7.
Gerstung M, Jolly C, Leshchiner I, Dentro S, Gonzalez S, Rosebrock D, et al.
Nature
. 2023 Jan;
614(7948):E42.
PMID: 36697833
No abstract available.
8.
Cmero M, Yuan K, Ong C, Schroder J, Corcoran N, Papenfuss T, et al.
Nat Commun
. 2022 Dec;
13(1):7568.
PMID: 36481724
No abstract available.
9.
Drews R, Hernando B, Tarabichi M, Haase K, Lesluyes T, Smith P, et al.
Nature
. 2022 Jun;
606(7916):976-983.
PMID: 35705807
Chromosomal instability (CIN) results in the accumulation of large-scale losses, gains and rearrangements of DNA. The broad genomic complexity caused by CIN is a hallmark of cancer; however, there is...
10.
Chaves-Urbano B, Hernando B, Garcia M, Macintyre G
Bioinformatics
. 2022 May;
38(14):3638-3641.
PMID: 35640971
Summary: Selecting the optimal cancer cell line for an experiment can be challenging given the diversity of lines available. Here, we present CNpare, which identifies similar cell line models based...