Gavin Hudson
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Explore the profile of Gavin Hudson including associated specialties, affiliations and a list of published articles.
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97
Citations
3245
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Recent Articles
11.
Floros V, Pyle A, Dietmann S, Wei W, Tang W, Irie N, et al.
Nat Cell Biol
. 2022 Dec;
25(1):194.
PMID: 36522542
No abstract available.
12.
Calabrese C, Pyle A, Griffin H, Coxhead J, Hussain R, Braund P, et al.
PLoS Genet
. 2022 Apr;
18(4):e1010068.
PMID: 35363781
Mitochondria are implicated in the pathogenesis of cardiovascular diseases (CVDs) but the reasons for this are not well understood. Maternally-inherited population variants of mitochondrial DNA (mtDNA) which affect all mtDNA...
13.
Bury A, Pyle A, Marcuccio F, Turnbull D, Vincent A, Hudson G, et al.
Anal Bioanal Chem
. 2022 Mar;
414(18):5483-5492.
PMID: 35233697
Intracellular heterogeneity contributes significantly to cellular physiology and, in a number of debilitating diseases, cellular pathophysiology. This is greatly influenced by distinct organelle populations and to understand the aetiology of...
14.
Pickett S, Deen D, Pyle A, Santibanez-Koref M, Hudson G
Mitochondrion
. 2022 Feb;
63:85-88.
PMID: 35167983
Interactions between the products of the nuclear and mitochondrial genomes are critical for the function of most eukaryotic cells. Recently the introduction of mitochondrial replacement therapy has raised the question...
15.
Smith A, Whitehall J, Bradshaw C, Gay D, Robertson F, Blain A, et al.
Nat Cancer
. 2022 Feb;
2(1):129.
PMID: 35121898
No abstract available.
16.
Szwedo A, Dalen I, Pedersen K, Camacho M, Backstrom D, Forsgren L, et al.
Mov Disord
. 2022 Feb;
37(5):1016-1027.
PMID: 35106798
Background: Common genetic variance in apolipoprotein E (APOE), β-glucocerebrosidase (GBA), microtubule-associated protein tau (MAPT), and α-synuclein (SNCA) has been linked to cognitive decline in Parkinson's disease (PD), although studies have...
17.
Chen C, Mossman E, Malko P, McDonald D, Blain A, Bone L, et al.
Mov Disord
. 2021 Nov;
37(2):302-314.
PMID: 34779538
Background: Mitochondrial dysfunction within neurons, particularly those of the substantia nigra, has been well characterized in Parkinson's disease and is considered to be related to the pathogenesis of this disorder....
18.
Bury A, Robertson F, Pyle A, Payne B, Hudson G
Methods Mol Biol
. 2021 Jun;
2277:433-447.
PMID: 34080167
In recent years, next-generation sequencing (NGS) has become a powerful tool for studying both inherited and somatic heteroplasmic mitochondrial DNA (mtDNA) variation. NGS has proved particularly powerful when combined with...
19.
Chen C, McDonald D, Blain A, Sachdeva A, Bone L, Smith A, et al.
NPJ Parkinsons Dis
. 2021 May;
7(1):39.
PMID: 33980828
Here we report the application of a mass spectrometry-based technology, imaging mass cytometry, to perform in-depth proteomic profiling of mitochondrial complexes in single neurons, using metal-conjugated antibodies to label post-mortem...
20.
Blyth U, Craciunas L, Hudson G, Choudhary M
Hum Reprod Update
. 2021 May;
27(5):866-884.
PMID: 33969392
Background: Miscarriage describes the spontaneous loss of pregnancy before the threshold of viability; the vast majority occur before 12 weeks of gestation. Miscarriage affects one in four couples and is...