Gautam Maulik
Overview
Explore the profile of Gautam Maulik including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
1510
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Recent Articles
1.
Bailey S, Miron P, Choi Y, Kochupurakkal B, Maulik G, Rodig S, et al.
Mol Cancer Res
. 2013 Dec;
12(3):408-420.
PMID: 24319068
Unlabelled: Breast cancers with HER2 overexpression are sensitive to drugs targeting the receptor or its kinase activity. HER2-targeting drugs are initially effective against HER2-positive breast cancer, but resistance inevitably occurs....
2.
Sen Banerjee S, Thirunavukkarasu M, Tipu Rishi M, Sanchez J, Maulik N, Maulik G
Toxicol Mech Methods
. 2012 Mar;
22(5):347-58.
PMID: 22424133
Prolyl hydroxylases belong to the family of iron- and 2-oxoglutamate-dependent dioxygenase enzyme. Several distinct prolyl hydroxylases have been identified. The hypoxia-inducible factor (HIF) prolyl hydroxylase termed prolyl hydroxylase domain (PHD)...
3.
Phytochemical antioxidants modulate mammalian cellular epigenome: implications in health and disease
Malireddy S, Kotha S, Secor J, Gurney T, Abbott J, Maulik G, et al.
Antioxid Redox Signal
. 2012 Mar;
17(2):327-39.
PMID: 22404530
Unlabelled: In living systems, the mechanisms of inheritance involving gene expression are operated by (i) the traditional model of genetics where the deoxyribonucleic acid (DNA) transcription and messenger ribonucleic acid...
4.
Selvaraju V, Joshi M, Suresh S, Sanchez J, Maulik N, Maulik G
Toxicol Mech Methods
. 2012 Mar;
22(5):330-5.
PMID: 22394340
In recent years, diabetes and its associated complications have come to represent a major public health concern. It is a complex disease characterized by multiple metabolic derangements and is known...
5.
Thirunavukkarasu M, Adluri R, Juhasz B, Samuel S, Zhan L, Kaur A, et al.
Funct Integr Genomics
. 2011 Nov;
12(3):501-14.
PMID: 22038056
Several potential sources of reactive oxygen species (ROS) in cells exist. One source is NADPH oxidase, which is especially important for superoxide radical production. Nox2 is a primary regulatory subunit...
6.
Adluri R, Thirunavukkarasu M, Zhan L, Maulik N, Svennevig K, Bagchi M, et al.
Cell Biochem Biophys
. 2011 Oct;
67(2):281-6.
PMID: 21960420
Circumstantial evidence frequently implicates oxygen-derived free radicals and oxidative stress as mediators of myocardial ischemia/reperfusion (I/R) injury. Therefore, external supplementation of natural antioxidants plays a main role as cardioprotective compounds....
7.
Adluri R, Thirunavukkarasu M, Rao Dunna N, Zhan L, Oriowo B, Takeda K, et al.
Antioxid Redox Signal
. 2010 Nov;
15(7):1789-97.
PMID: 21083501
Hypoxia-inducible transcription factor (HIF)-prolyl hydroxylases domain (PHD-1-3) are oxygen sensors that regulate the stability of the HIFs in an oxygen-dependent manner. Suppression of PHD enzymes leads to stabilization of HIFs...
8.
Adluri R, Thirunavukkarasu M, Zhan L, Akita Y, Samuel S, Otani H, et al.
J Mol Cell Cardiol
. 2010 Nov;
50(1):239-47.
PMID: 21074540
Oxidative stress plays a crucial role in disruption of neovascularization by alterations in thioredoxin 1 (Trx1) expression and its interaction with other proteins after myocardial infarction (MI). We previously showed...
9.
Bueno R, De Rienzo A, Dong L, Gordon G, Hercus C, Richards W, et al.
PLoS One
. 2010 May;
5(5):e10612.
PMID: 20485525
The current paradigm for elucidating the molecular etiology of cancers relies on the interrogation of small numbers of genes, which limits the scope of investigation. Emerging second-generation massively parallel DNA...
10.
Adluri R, Zhan L, Bagchi M, Maulik N, Maulik G
Mol Cell Biochem
. 2010 Mar;
340(1-2):73-80.
PMID: 20213262
Calcium is an essential mineral to support bone health and serves as a major therapeutic intervention to prevent and delay the incidence of osteoporosis. Many individuals do not obtain the...