Ram Sudheer Adluri
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Explore the profile of Ram Sudheer Adluri including associated specialties, affiliations and a list of published articles.
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10
Citations
175
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Recent Articles
1.
Selvaraju V, Parinandi N, Adluri R, Goldman J, Hussain N, Sanchez J, et al.
Antioxid Redox Signal
. 2013 Sep;
20(16):2631-65.
PMID: 23992027
Significance: In this review, we have discussed the efficacy and effect of small molecules that act as prolyl hydroxylase domain inhibitors (PHDIs). The use of these compounds causes upregulation of...
2.
Oriowo B, Thirunavukkarasu M, Selvaraju V, Adluri R, Zhan L, Takeda K, et al.
Curr Pharm Des
. 2013 Aug;
20(9):1305-10.
PMID: 23978105
The key oxygen sensing molecules, Prolyl-hydroxylase domain 1-3 enzymes (PHD1-3), regulate hypoxia-inducible factor (HIF) under hypoxia. In the settings of cardiomyopathy and ischemia-reperfusion injury, PHD3 expression is elevated, resulting in...
3.
Marimuthu S, Adluri R, Rajagopalan R, Menon V
J Basic Clin Physiol Pharmacol
. 2012 Dec;
24(1):59-66.
PMID: 23241587
Background: The present study aimed to evaluate the antihyperlipidemic effect of ferulic acid (FA) on carbon tetrachloride (CCl4)-treated rats. Methods: Female albino rats of the Wistar strain were used in...
4.
Adluri R, Thirunavukkarasu M, Zhan L, Rao Dunna N, Akita Y, Selvaraju V, et al.
PLoS One
. 2012 Apr;
7(3):e34790.
PMID: 22523530
Oxidative stress plays a critical role in the pathophysiology of cardiac failure, including the modulation of neovascularization following myocardial infarction (MI). Redox molecules thioredoxin (Trx) and glutaredoxin (Grx) superfamilies actively...
5.
Thirunavukkarasu M, Adluri R, Juhasz B, Samuel S, Zhan L, Kaur A, et al.
Funct Integr Genomics
. 2011 Nov;
12(3):501-14.
PMID: 22038056
Several potential sources of reactive oxygen species (ROS) in cells exist. One source is NADPH oxidase, which is especially important for superoxide radical production. Nox2 is a primary regulatory subunit...
6.
Adluri R, Thirunavukkarasu M, Zhan L, Maulik N, Svennevig K, Bagchi M, et al.
Cell Biochem Biophys
. 2011 Oct;
67(2):281-6.
PMID: 21960420
Circumstantial evidence frequently implicates oxygen-derived free radicals and oxidative stress as mediators of myocardial ischemia/reperfusion (I/R) injury. Therefore, external supplementation of natural antioxidants plays a main role as cardioprotective compounds....
7.
Adluri R, Thirunavukkarasu M, Rao Dunna N, Zhan L, Oriowo B, Takeda K, et al.
Antioxid Redox Signal
. 2010 Nov;
15(7):1789-97.
PMID: 21083501
Hypoxia-inducible transcription factor (HIF)-prolyl hydroxylases domain (PHD-1-3) are oxygen sensors that regulate the stability of the HIFs in an oxygen-dependent manner. Suppression of PHD enzymes leads to stabilization of HIFs...
8.
Adluri R, Thirunavukkarasu M, Zhan L, Akita Y, Samuel S, Otani H, et al.
J Mol Cell Cardiol
. 2010 Nov;
50(1):239-47.
PMID: 21074540
Oxidative stress plays a crucial role in disruption of neovascularization by alterations in thioredoxin 1 (Trx1) expression and its interaction with other proteins after myocardial infarction (MI). We previously showed...
9.
Adluri R, Zhan L, Bagchi M, Maulik N, Maulik G
Mol Cell Biochem
. 2010 Mar;
340(1-2):73-80.
PMID: 20213262
Calcium is an essential mineral to support bone health and serves as a major therapeutic intervention to prevent and delay the incidence of osteoporosis. Many individuals do not obtain the...
10.
Adluri R, Nagarajan D, Periyaswamy V, Venugopal P
Fundam Clin Pharmacol
. 2008 Oct;
22(5):557-67.
PMID: 18844727
In the present study, ferulic acid (FA), a naturally occurring nutritional compound, was investigated for its protective effect against nicotine-induced toxicity in a dose dependent manner. The toxicity was induced...