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Gary Sisson

Explore the profile of Gary Sisson including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 741
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Recent Articles
1.
Holay N, Kennedy B, Murphy J, Konda P, Giacomantonio M, Brauer-Chapin T, et al.
Front Immunol . 2023 Feb; 13:1047661. PMID: 36818473
CD8 T cells play a central role in antiviral immunity. Type I interferons are among the earliest responders after virus exposure and can cause extensive reprogramming and antigen-independent bystander activation...
2.
Ostadgavahi A, Booth R, Sisson G, McMullen N, Warhuus M, Robertson P, et al.
J Infect Dev Ctries . 2021 Jun; 15(5):653-656. PMID: 34106888
Understanding the efficacy and durability of heterologous immunization schedules against SARS-CoV-2 is critical, as supply demands and vaccine choices become significant issues in the global vaccination strategy. Here we characterize...
3.
Ha M, Delpeut S, Noyce R, Sisson G, Black K, Lin L, et al.
J Virol . 2017 Sep; 91(23). PMID: 28904193
The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-phenylacetyl amino-benzamide (AS-48) have similar efficacies in blocking membrane fusion and syncytium formation mediated by measles virus (MeV). Other homologues, such...
4.
Delpeut S, Sisson G, Black K, Richardson C
J Virol . 2017 Mar; 91(10). PMID: 28250131
Measles virus (MeV) is a member of the family that causes a highly contagious respiratory disease but has emerged as a promising oncolytic platform. Previous studies of MeV entry focused...
5.
Noyce R, Bondre D, Ha M, Lin L, Sisson G, Tsao M, et al.
PLoS Pathog . 2011 Sep; 7(8):e1002240. PMID: 21901103
Vaccine and laboratory adapted strains of measles virus can use CD46 as a receptor to infect many human cell lines. However, wild type isolates of measles virus cannot use CD46,...
6.
Gong Y, Tian X, Sutherland T, Sisson G, Mai J, Ling J, et al.
Microbiology (Reading) . 2009 Jul; 155(Pt 10):3322-3332. PMID: 19608608
Streptococcus mutans in dental biofilms is regularly exposed to cycles of acidic pH during the ingestion of fermentable dietary carbohydrates. The ability of S. mutans to tolerate low pH is...
7.
Li Y, Tian X, Layton G, Norgaard C, Sisson G
Microbiology (Reading) . 2008 Oct; 154(Pt 11):3256-3265. PMID: 18957580
The genome of Streptococcus mutans harbours 13 two-component signal transduction systems (TCSTSs). Of these, a peptide-mediated quorum-sensing system, ComCDE, and the HK/RR11 two-component system are well known to regulate several...
8.
St Maurice M, Cremades N, Croxen M, Sisson G, Sancho J, Hoffman P
J Bacteriol . 2007 May; 189(13):4764-73. PMID: 17468253
Pyruvate-dependent reduction of NADP has been demonstrated in cell extracts of the human gastric pathogen Helicobacter pylori. However, NADP is not a substrate of purified pyruvate:ferredoxin oxidoreductase (PFOR), suggesting that...
9.
Hoffman P, Sisson G, Croxen M, Welch K, Harman W, Cremades N, et al.
Antimicrob Agents Chemother . 2006 Dec; 51(3):868-76. PMID: 17158936
Nitazoxanide (NTZ) exhibits broad-spectrum activity against anaerobic bacteria and parasites and the ulcer-causing pathogen Helicobacter pylori. Here we show that NTZ is a noncompetitive inhibitor (K(i), 2 to 10 microM)...
10.
Croxen M, Sisson G, Melano R, Hoffman P
J Bacteriol . 2006 Mar; 188(7):2656-65. PMID: 16547053
The location of Helicobacter pylori in the gastric mucosa of mammals is defined by natural pH gradients within the gastric mucus, which are more alkaline proximal to the mucosal epithelial...