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Ryan S Noyce

Explore the profile of Ryan S Noyce including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 1341
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Recent Articles
1.
Lin Y, Evans D, Noyce R
Methods Mol Biol . 2024 Dec; 2860:97-114. PMID: 39621263
The low-frequency natural recombination that is detected in poxvirus-infected cells has long been used to genetically modify poxviruses. Such recombinant poxviruses have found many applications as vaccines for preventing infectious...
2.
Loeb K, Milner K, Lemaille C, Martens B, Stein D, Lajoie J, et al.
Emerg Infect Dis . 2024 Aug; 30(9):1944-1947. PMID: 39174040
We identified a cluster of mpox exposures among key populations in Kenya through retrospective serologic screening. We identified strong seropositivity among sex workers and gay, bisexual, and other men who...
3.
Umer B, Noyce R, Kieser Q, Favis N, Shenouda M, Rans K, et al.
PLoS One . 2024 Mar; 19(3):e0298437. PMID: 38498459
Ionizing radiation (IR) and oncolytic viruses are both used to treat cancer, and the effectiveness of both agents depends upon stimulating an immune response against the tumor. In this study...
4.
Miranzadeh Mahabadi H, Lin Y, Ogando N, Moussa E, Mohammadzadeh N, Julien O, et al.
Proc Natl Acad Sci U S A . 2024 Feb; 121(8):e2315653121. PMID: 38346199
Monkeypox virus (MPXV) infections in humans cause neurological disorders while studies of MPXV-infected animals indicate that the virus penetrates the brain. Pyroptosis is an inflammatory type of regulated cell death,...
5.
Awasthi M, Macaluso A, Myscofski D, Prigge J, Koide F, Noyce R, et al.
Vaccines (Basel) . 2023 Nov; 11(11). PMID: 38006014
TNX-1800 is a synthetically derived live recombinant chimeric horsepox virus (rcHPXV) vaccine candidate expressing Wuhan SARS-CoV-2 spike (S) protein. The primary objective of this study was to evaluate the immunogenicity...
6.
Awasthi M, Macaluso A, Goebel S, Luea E, Noyce R, Nasar F, et al.
Viruses . 2023 Oct; 15(10). PMID: 37896908
TNX-1800 is a preclinical stage synthetic-derived live attenuated chimeric horsepox virus vaccine engineered to express the SARS-CoV-2 spike (S) gene. The objectives of this study were to assess the safety,...
7.
Storozynsky Q, Agopsowicz K, Noyce R, Bukhari A, Han X, Snyder N, et al.
Cancer Lett . 2023 Apr; 562:216169. PMID: 37061120
Glioblastoma (GB) is a malignant and immune-suppressed brain cancer that remains incurable despite the current standard of care. Radiotherapy is a mainstay of GB treatment, however invasive cancer cells outside...
8.
Noyce R, Westfall L, Fogarty S, Gilbert K, Mpanju O, Stillwell H, et al.
Viruses . 2023 Feb; 15(2). PMID: 36851570
The ongoing global Monkeypox outbreak that started in the spring of 2022 has reinforced the importance of protecting the population using live virus vaccines based on the vaccinia virus (VACV)....
9.
Viveiros A, Noyce R, Gheblawi M, Colombo D, Bilawchuk L, Clemente-Casares X, et al.
Am J Physiol Heart Circ Physiol . 2022 Nov; 323(6):H1262-H1269. PMID: 36367689
Myocardial pathologies resulting from SARS-CoV-2 infections are consistently rising with mounting case rates and reinfections; however, the precise global burden is largely unknown and will have an unprecedented impact. Understanding...
10.
Meier-Stephenson F, Meier-Stephenson V, Carter M, Meek A, Wang Y, Pan L, et al.
Alzheimers Dement (N Y) . 2022 Apr; 8(1):e12283. PMID: 35415204
Introduction: Alzheimer's disease (AD) is characterized by neurotoxic immuno-inflammation concomitant with cytotoxic oligomerization of amyloid beta (Aβ) and tau, culminating in concurrent, interdependent immunopathic and proteopathic pathogeneses. Methods: We performed...