Gary P Brennan
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Explore the profile of Gary P Brennan including associated specialties, affiliations and a list of published articles.
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38
Citations
750
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Recent Articles
1.
Harnett A, Mathoux J, Wilson M, Heiland M, Mamad O, Srinivas S, et al.
Eur J Neurosci
. 2024 Aug;
60(6):5266-5283.
PMID: 39149798
Epilepsy is a neurological disease characterised by recurrent seizures with complex aetiology. Temporal lobe epilepsy, the most common form in adults, can be acquired following brain insults including trauma, stroke,...
2.
Lau K, Nguyen N, Kesavan J, Langa E, Fanning K, Brennan G, et al.
Brain Commun
. 2024 Jan;
6(1):fcad355.
PMID: 38204971
MicroRNAs have emerged as important regulators of the gene expression landscape in temporal lobe epilepsy. The mechanisms that control microRNA levels and influence target choice remain, however, poorly understood. RNA...
3.
Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy
Brindley E, Heiland M, Mooney C, Diviney M, Mamad O, Hill T, et al.
Front Mol Neurosci
. 2023 Oct;
16:1230942.
PMID: 37808470
The diagnosis of epilepsy is complex and challenging and would benefit from the availability of molecular biomarkers, ideally measurable in a biofluid such as blood. Experimental and human epilepsy are...
4.
de Diego-Garcia L, Brennan G, Auer T, Menendez-Mendez A, Parras A, Martin-Gil A, et al.
Epilepsia
. 2023 Aug;
64(10):2827-2840.
PMID: 37543852
Objective: Posttranscriptional mechanisms are increasingly recognized as important contributors to the formation of hyperexcitable networks in epilepsy. Messenger RNA (mRNA) polyadenylation is a key regulatory mechanism governing protein expression by...
5.
Engel T, Brennan G, Soreq H
Front Mol Neurosci
. 2022 Dec;
15:1064121.
PMID: 36483570
No abstract available.
6.
Quinlan S, Henke C, Brennan G, Henshall D, Jimenez-Mateos E
Methods Mol Biol
. 2022 Nov;
2595:93-100.
PMID: 36441456
MicroRNAs are key posttranscriptional regulators of protein levels in cells. The brain is particularly enriched in microRNAs, and important roles have been demonstrated for these noncoding RNAs in various neurological...
7.
Leavy A, Brennan G, Jimenez-Mateos E
Biomedicines
. 2022 Nov;
10(11).
PMID: 36359259
Brain development occurs until adulthood, with time-sensitive processes happening during embryo development, childhood, and puberty. During early life and childhood, dynamic changes in the brain are critical for physiological brain...
8.
Bindila L, Eid T, Mills J, Hildebrand M, Brennan G, Masino S, et al.
Epilepsia Open
. 2022 Oct;
PMID: 36259125
The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines. This...
9.
van Vliet E, Hildebrand M, Mills J, Brennan G, Eid T, Masino S, et al.
Epilepsia Open
. 2022 Aug;
PMID: 35950645
The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines. The...
10.
Mathoux J, Henshall D, Brennan G
Front Cell Neurosci
. 2021 Jun;
15:671932.
PMID: 34093133
RNA modifications have emerged as an additional layer of regulatory complexity governing the function of almost all species of RNA. -methyladenosine (mA), the addition of methyl groups to adenine residues,...