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Garry P Morgan

Explore the profile of Garry P Morgan including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 765
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Recent Articles
1.
Basta T, Morgan G, OToole E, Rao N, Savas J, Stowell M
Methods Mol Biol . 2022 Jul; 2473:129-139. PMID: 35819763
Electron tomography of the chemical synapse provides important architectural information regarding the organization of synaptic organelles including synaptic vesicles, Nissl bodies, and early endosomes. Here, we describe methods for the...
2.
Hark T, Rao N, Castillon C, Basta T, Smukowski S, Bao H, et al.
Cell Syst . 2020 Dec; 12(2):141-158.e9. PMID: 33326751
Compromised protein homeostasis underlies accumulation of plaques and tangles in Alzheimer's disease (AD). To observe protein turnover at early stages of amyloid beta (Aβ) proteotoxicity, we performed pulse-chase proteomics on...
3.
Chaparro Sosa A, de Oliveira da Silva S, Morgan G, Schwartz D, Kaar J
J Phys Chem Lett . 2020 Aug; 11(17):7417-7422. PMID: 32803986
While many approaches to reduce fibrillation of amyloid-β (Aβ) have been aimed at slowing fibril formation, the degradation of fibrils remains challenging. We provide insight into fibril degradation as well...
4.
Soh A, van Dam T, Stemm-Wolf A, Pham A, Morgan G, OToole E, et al.
J Cell Biol . 2019 Nov; 219(1). PMID: 31740506
Multi-ciliary arrays promote fluid flow and cellular motility using the polarized and coordinated beating of hundreds of motile cilia. Tetrahymena basal bodies (BBs) nucleate and position cilia, whereby BB-associated striated...
5.
Maity K, Heumann J, McGrath A, Kopcho N, Hsu P, Lee C, et al.
Proc Natl Acad Sci U S A . 2019 Jun; 116(28):14309-14318. PMID: 31227607
Sensing and responding to environmental water deficiency and osmotic stresses are essential for the growth, development, and survival of plants. Recently, an osmolality-sensing ion channel called OSCA1 was discovered that...
6.
Pentakota S, Zhou K, Smith C, Maffini S, Petrovic A, Morgan G, et al.
Elife . 2017 Dec; 6. PMID: 29280735
Centromere protein (CENP) A, a histone H3 variant, is a key epigenetic determinant of chromosome domains known as centromeres. Centromeres nucleate kinetochores, multi-subunit complexes that capture spindle microtubules to promote...
7.
Ve T, Vajjhala P, Hedger A, Croll T, DiMaio F, Horsefield S, et al.
Nat Struct Mol Biol . 2017 Aug; 24(9):743-751. PMID: 28759049
Toll-like receptor (TLR) signaling is a key innate immunity response to pathogens. Recruitment of signaling adapters such as MAL (TIRAP) and MyD88 to the TLRs requires Toll/interleukin-1 receptor (TIR)-domain interactions,...
8.
Harper C, Papadopulos A, Martin S, Matthews D, Morgan G, Nguyen T, et al.
Sci Rep . 2016 Jan; 6:19654. PMID: 26805017
Neuronal communication relies on synaptic vesicles undergoing regulated exocytosis and recycling for multiple rounds of fusion. Whether all synaptic vesicles have identical protein content has been challenged, suggesting that their...
9.
Kettle E, Page S, Morgan G, Malladi C, Wong C, Boadle R, et al.
Traffic . 2015 Sep; 16(11):1174-92. PMID: 26399547
Cytokinesis is the final stage of cell division and produces two independent daughter cells. Vesicles derived from internal membrane stores, such as the Golgi, lysosomes, and early and recycling endosomes...
10.
Lo H, Nixon S, Hall T, Cowling B, Ferguson C, Morgan G, et al.
J Cell Biol . 2015 Sep; 210(5):833-49. PMID: 26323694
Dysfunction of caveolae is involved in human muscle disease, although the underlying molecular mechanisms remain unclear. In this paper, we have functionally characterized mouse and zebrafish models of caveolae-associated muscle...