Ganesh A Sable
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Explore the profile of Ganesh A Sable including associated specialties, affiliations and a list of published articles.
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8
Citations
21
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Recent Articles
1.
Mhetre A, Sreedhar E, Dubey R, Sable G, Lee H, Yang H, et al.
RSC Adv
. 2022 May;
9(50):29023-29036.
PMID: 35528410
A diverse series of compounds (18a-x) were synthesized from ()-1-(chloromethyl)-8-methoxy-2,3-dihydro-1-benzo[]indol-5-ol (-MCBI) and benzoselenophene or heteroaromatic acids. These new compounds were evaluated for their cytotoxicity against the human gastric NCI-N87 and...
2.
Habeshian S, Sable G, Schuttel M, Merz M, Heinis C
ACS Chem Biol
. 2022 Jan;
17(1):181-186.
PMID: 35015522
The synthesis of large numbers of cyclic peptides─required, for example, in screens for drug development─is currently limited by the need of chromatographic purification of individual peptides. Herein, we have developed...
3.
Lee I, Kim E, Choi S, Kim D, Hong W, Choi J, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(14).
PMID: 33795513
Plants sense and integrate diverse stimuli to determine the timing for germination. A smoke compound, 3,4,5-trimethylfuran-2()-one (trimethylbutenolide, TMB), has been identified to inhibit the seed germination of higher plants. To...
4.
Lee Y, Heo J, Jeong H, Hong K, Kwon D, Shin M, et al.
Angew Chem Int Ed Engl
. 2020 Oct;
59(40):17548-17555.
PMID: 33026161
Aberrantly elevated steroid receptor coactivator-1 (SRC-1) expression and activity are strongly correlated with cancer progression and metastasis. Here we report, for the first time, the development of a proteolysis targeting...
5.
Lee K, Sable G, Shin M, Lim H
Biopolymers
. 2019 Jun;
110(6):e23289.
PMID: 31150108
Peptoids, oligomers of N-substituted glycines, have been attracting increasing interest due to their advantageous properties as peptidomimetics. However, due to the lack of chiral centers and amide hydrogen atoms, peptoids,...
6.
Sable G, Lee K, Lim H
Molecules
. 2019 Jan;
24(1).
PMID: 30621297
The development of peptidomimetic foldamers that can form well-defined folded structures is highly desirable yet challenging. We previously reported on α-ABpeptoids, oligomers of -alkylated β²-homoalanines and found that due to...
7.
Sable G, Lee K, Shin M, Lim H
Org Lett
. 2018 Apr;
20(9):2526-2529.
PMID: 29659283
A novel submonomer solid-phase synthetic method for α-ABpeptoid oligomers is reported. Iterative submonomer coupling and Fukuyama-Mitsunobu alkylation enable facile, divergent synthesis of α-ABpeptoid oligomers substituted with chemically diverse side chains...
8.
Sable G, Lim D
J Org Chem
. 2015 Jul;
80(15):7486-94.
PMID: 26171914
Triostin A is a symmetric bicyclic depsipeptide with very potent antitumoral activity because of its bisintercalation into DNA. In this study, we report a new synthetic strategy that exploits a...