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Gabriele Holzlwimmer

Explore the profile of Gabriele Holzlwimmer including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 726
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Recent Articles
1.
Herrera M, Mezheyeuski A, Villabona L, Corvigno S, Strell C, Klein C, et al.
Cancers (Basel) . 2020 Nov; 12(11). PMID: 33153037
Inter-case variations in immune cell and fibroblast composition are associated with prognosis in solid tumors, including colon cancer. A series of experimental studies suggest immune-modulatory roles of marker-defined fibroblast populations,...
2.
Muckenhuber A, Babitzki G, Thomas M, Holzlwimmer G, Zajac M, Jesinghaus M, et al.
Pancreas . 2016 Jan; 45(8):1167-74. PMID: 26825865
Objectives: Comprehensive assessment of cMET and HER family receptor tyrosine kinases expression, changes of expression during metastatic progression, amplification status of the MET gene, and correlations with patient characteristics in...
3.
Meneses-Lorente G, Friess T, Kolm I, Holzlwimmer G, Bader S, Meille C, et al.
Cancer Chemother Pharmacol . 2015 Feb; 75(4):837-50. PMID: 25702049
Purpose: RG7116 is a novel anti-HER3 therapeutic antibody that inhibits HER3 signalling and induces antibody-dependent cellular cytotoxicity of tumor cells due to a glycoengineered antibody Fc moiety. We investigated the...
4.
van Scheltinga A, Lub-de Hooge M, Abiraj K, Schroder C, Pot L, Bossenmaier B, et al.
MAbs . 2014 May; 6(4):1051-8. PMID: 24870719
The humanized monoclonal antibody with high affinity for the human epidermal growth factor receptor (HER) 3, RG7116, is a glycoengineered, IgG1 class antibody. By labeling RG7116 with zirconium-89 ((89)Zr) we...
5.
Herting F, Friess T, Bader S, Muth G, Holzlwimmer G, Rieder N, et al.
Leuk Lymphoma . 2013 Dec; 55(9):2151-5160. PMID: 24304419
Obinutuzumab (GA101) is a novel glycoengineered type II CD20 antibody in development for non-Hodgkin lymphoma. We compared the anti-tumor activity of obinutuzumab and rituximab in preclinical studies using subcutaneous Z138...
6.
Dalke C, Holzlwimmer G, Calzada-Wack J, Quintanilla-Martinez L, Atkinson M, Rosemann M
J Radiat Res . 2012 Jun; 53(3):343-52. PMID: 22739003
Genetic factors can modify susceptibility to the carcinogenic effect of ionising radiation. To establish if radioiodine-induced thyroid cancer is similarly genetically influenced, we studied F1 hybrid crosses between inbred mouse...
7.
Saraste A, Laitinen I, Weidl E, Wildgruber M, Weber A, Nekolla S, et al.
J Nucl Cardiol . 2012 Apr; 19(4):775-84. PMID: 22527796
Background: Expression of α(v)β(3) integrin has been proposed as a marker for atherosclerotic lesion inflammation. We studied whether diet intervention reduces uptake of α(v)β(3) integrin-targeted positron emission tomography tracer (18)F-galacto-RGD...
8.
Hoellein A, Graf S, Bassermann F, Schoeffmann S, Platz U, Holzlwimmer G, et al.
Mol Cell Biol . 2012 Apr; 32(13):2416-27. PMID: 22508990
Cks1 is an activator of the SCF(Skp2) ubiquitin ligase complex that targets the cell cycle inhibitor p27(Kip1) for degradation. The loss of Cks1 results in p27(Kip1) accumulation and decreased proliferation...
9.
Hormannsperger G, Clavel T, Hoffmann M, Reiff C, Kelly D, Loh G, et al.
J Clin Gastroenterol . 2010 Jun; 44 Suppl 1:S10-5. PMID: 20562631
Background And Aim: Inflammatory bowel diseases (IBD) are immune-mediated chronic diseases that are characterized by an overreaction of the intestinal immune system to the intestinal microbiota. VSL#3, a mixture of...
10.
Shyla A, Holzlwimmer G, Calzada-Wack J, Bink K, Tischenko O, Guilly M, et al.
Int J Cancer . 2009 Oct; 126(10):2362-72. PMID: 19876893
Pheochromocytomas are neoplasias of neural crest origin that arise from the chromaffin cells of the adrenal medulla. Pheochromocytomas arise with complete penetrance in rats homozygous for a germ-line frameshift mutation...