Dirk Haller
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Explore the profile of Dirk Haller including associated specialties, affiliations and a list of published articles.
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213
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8383
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Recent Articles
1.
Metwaly A, Kriaa A, Hassani Z, Carraturo F, Druart C, Arnauts K, et al.
Nat Rev Gastroenterol Hepatol
. 2025 Mar;
PMID: 40033063
The gut microbiome comprises trillions of microorganisms and profoundly influences human health by modulating metabolism, immune responses and neuronal functions. Disruption in gut microbiome composition is implicated in various inflammatory...
2.
Misselwitz B, Haller D
Inn Med (Heidelb)
. 2025 Jan;
66(2):146-155.
PMID: 39870907
Background: The intestinal microbiota comprises all living microorganisms in the gastrointestinal tract and is crucial for its function. Clinical observations and laboratory findings confirm a central role of the microbiota...
3.
Wortmann E, Wylensek D, Basic M, Hermeling S, Bleich A, Haller D, et al.
Microbiome Res Rep
. 2025 Jan;
3(4):44.
PMID: 39741948
The gut microbiota is implicated in the development of intestinal tumors. Furthermore, Western diet is a risk factor for colorectal cancer and induces alterations in both the microbiota and bile...
4.
Heimes H, Hacker D, Omer H, van der Veen D, Kiessling S, Haller D
STAR Protoc
. 2024 Nov;
5(4):103419.
PMID: 39487984
Chemostat systems can be used to cultivate complex intestinal microbial communities ex vivo. Here, we present a protocol to transfer bacteria from human fecal material into chemostat systems as well...
5.
Hacker D, Siebert K, Smith B, Kohler N, Riva A, Mahapatra A, et al.
Cell Host Microbe
. 2024 Oct;
32(11):2019-2034.e8.
PMID: 39461337
Exclusive enteral nutrition (EEN) is a first-line therapy for pediatric Crohn's disease (CD), but protective mechanisms remain unknown. We established a prospective pediatric cohort to characterize the function of fecal...
6.
Remke M, Groll T, Metzler T, Urbauer E, Kovilein J, Schnalzger T, et al.
Exp Mol Pathol
. 2024 Oct;
140:104938.
PMID: 39418944
Background And Aims: Histomorphology is a powerful and cost-efficient tool for evaluating inflammatory and neoplastic conditions. Inflammatory bowel disease (IBD) is a widespread condition with globally rising incidences, and a...
7.
Fasano A, Chassaing B, Haller D, Flores Ventura E, Carmen-Collado M, Pastor N, et al.
Gut Microbes
. 2024 Aug;
16(1):2392009.
PMID: 39161102
Here, we explored the vast potential of microbiome-based interventions in preventing and managing non-communicable diseases including obesity, diabetes, allergies, celiac disease, inflammatory bowel diseases, malnutrition, and cardiovascular diseases across different...
8.
Radani N, Metwaly A, Reitmeier S, Baumeister T, Ingermann J, Horstmann J, et al.
Gastro Hep Adv
. 2024 Aug;
1(5):755-766.
PMID: 39131856
Background And Aims: Esophageal adenocarcinoma (EAC) incidence has risen dramatically in the Western countries over the past decades. The underlying reasons are incompletely understood, and shifts in the esophageal microbiome...
9.
Hemmati M, Wudy S, Hackbarth F, Mittermeier-Klessinger V, Coleman O, Haller D, et al.
J Proteome Res
. 2024 Jul;
23(8):3124-3140.
PMID: 39052308
A multimetabo-lipid-prote-omics workflow was developed to characterize the molecular interplay within proximal (PC) and distal (DC) colonic epithelium of healthy mice. This multiomics data set lays the foundation to better...
10.
Urbauer E, Aguanno D, Mindermann N, Omer H, Metwaly A, Krammel T, et al.
Cell Host Microbe
. 2024 Jul;
32(8):1347-1364.e10.
PMID: 39013472
Mitochondrial dysfunction is associated with inflammatory bowel diseases (IBDs). To understand how microbial-metabolic circuits contribute to intestinal injury, we disrupt mitochondrial function in the epithelium by deleting the mitochondrial chaperone,...