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Gabriel Ichim

Explore the profile of Gabriel Ichim including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 1478
Followers 0
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Recent Articles
1.
Hernandez C, Verzeroli C, Roca-Suarez A, Farca-Luna A, Tonon L, Esteban-Fabro R, et al.
JHEP Rep . 2024 Dec; 7(1):101245. PMID: 39717507
Background & Aims: Owing to unexplained interpatient variation and treatment failure in hepatocellular carcinoma (HCC), novel therapeutic approaches remain an urgent clinical need. Hepatic neurons, belonging to the autonomic nervous...
2.
Nadjar J, Monnier S, Bastien E, Huber A, Oddou C, Bardoulet L, et al.
Sci Signal . 2024 Apr; 17(833):eabn8003. PMID: 38652763
Inflammasomes are multiprotein platforms that control caspase-1 activation, which process the inactive precursor forms of the inflammatory cytokines IL-1β and IL-18, leading to an inflammatory type of programmed cell death...
3.
Berthenet K, Aimontche E, El Mrini S, Briere J, Pion N, Iacono I, et al.
Sci Rep . 2024 Feb; 14(1):3768. PMID: 38355966
Neuroblastoma (NB) is the most common pediatric tumor and is currently treated by several types of therapies including chemotherapies, such as bortezomib treatment. However, resistance to bortezomib is frequently observed...
4.
Albaret M, Aimontche E, Bendriss-Vermare N, Diaz J, Gil C, Hedjam J, et al.
Bull Cancer . 2023 Oct; 110(12):1332-1342. PMID: 37806862
No abstract available.
5.
Piecyk M, Triki M, Laval P, Duret C, Fauvre J, Cussonneau L, et al.
Mol Oncol . 2023 Jul; 18(9):2111-2135. PMID: 37452637
Nutrient availability is a key determinant of tumor cell behavior. While nutrient-rich conditions favor proliferation and tumor growth, scarcity, and particularly glutamine starvation, promotes cell dedifferentiation and chemoresistance. Here, linking...
6.
Popgeorgiev N, Gil C, Berthenet K, Bertolin G, Ichim G
Semin Cell Dev Biol . 2023 Jul; 156:58-65. PMID: 37438211
Membrane structural integrity is essential for optimal mitochondrial function. These organelles produce the energy needed for all vital processes, provided their outer and inner membranes are intact. This prevents the...
7.
Martin N, Popgeorgiev N, Ichim G, Bernard D
Nat Rev Mol Cell Biol . 2023 Mar; 24(8):517-518. PMID: 36869150
No abstract available.
8.
Nicholls P, Pack T, Urs N, Kumar S, Zhou Y, Ichim G, et al.
eNeuro . 2023 Jan; 9(5). PMID: 36635920
The protease caspase-3 is a key mediator of apoptotic programmed cell death. But weak or transient caspase activity can contribute to neuronal differentiation, axonal pathfinding, and synaptic long-term depression. Despite...
9.
Coursier D, Coulette D, Leman H, Grenier E, Ichim G
Apoptosis . 2022 Nov; 28(3-4):326-334. PMID: 36346539
As a cellular intrinsic mechanism leading to cellular demise, apoptosis was thoroughly characterized from a mechanistic perspective. Nowadays there is an increasing interest in describing the non-cell autonomous or community...
10.
Saier L, Ribeiro J, Daunizeau T, Houssin A, Ichim G, Barette C, et al.
Int J Mol Sci . 2022 Oct; 23(20). PMID: 36293074
Metastases are the main cause of death in cancer patients, and platelets are largely known for their contribution in cancer progression. However, targeting platelets is highly challenging given their paramount...