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Gabor E Tusnady

Explore the profile of Gabor E Tusnady including associated specialties, affiliations and a list of published articles. Areas
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Articles 56
Citations 1513
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Recent Articles
1.
Dobson L, Tusnady G, Tompa P
Brief Bioinform . 2025 Mar; 26(2). PMID: 40067116
AlphaFold2 changed structural biology by providing high-quality structure predictions for all possible proteins. Since its inception, a plethora of applications were built on AlphaFold2, expediting discoveries in virtually all areas...
2.
Ficho E, Pancsa R, Magyar C, Kalman Z, Schad E, Nemeth B, et al.
Nucleic Acids Res . 2024 Nov; 53(D1):D487-D494. PMID: 39526403
While the majority of proteins with available structures are able to fold independently and mediate interactions only after acquiring their folded state, a subset of the known protein complexes contains...
3.
Jambrich M, Tusnady G, Dobson L
Sci Rep . 2023 Nov; 13(1):20283. PMID: 37985809
AlphaFold2 (AF2) provides a 3D structure for every known or predicted protein, opening up new prospects for virtually every field in structural biology. However, working with transmembrane protein molecules pose...
4.
Tusnady G, Zeke A, Kalman Z, Fatoux M, Ricard-Blum S, Gibson T, et al.
Database (Oxford) . 2023 Nov; 2023. PMID: 37935582
Leishmaniasis is a detrimental disease causing serious changes in quality of life and some forms can lead to death. The disease is spread by the parasite Leishmania transmitted by sandfly...
5.
Dobson L, Gerdan C, Tusnady S, Szekeres L, Kuffa K, Lango T, et al.
Nucleic Acids Res . 2023 Oct; 52(D1):D572-D578. PMID: 37870462
The UNIfied database of TransMembrane Proteins (UniTmp) is a comprehensive and freely accessible resource of transmembrane protein structural information at different levels, from localization of protein segments, through the topology...
6.
Lango T, Kuffa K, Toth G, Turiak L, Drahos L, Tusnady G
Int J Mol Sci . 2023 Jan; 24(1). PMID: 36613715
Cell surface proteins, including transmembrane and other surface-anchored proteins, play a key role in several critical cellular processes and have a strong diagnostic value. The development of quick and robust...
7.
Dobson L, Szekeres L, Gerdan C, Lango T, Zeke A, Tusnady G
Nucleic Acids Res . 2022 Nov; 51(D1):D517-D522. PMID: 36318239
AI-driven protein structure prediction, most notably AlphaFold2 (AF2) opens new frontiers for almost all fields of structural biology. As traditional structure prediction methods for transmembrane proteins were both complicated and...
8.
Bakos E, Nemet O, Kucsma N, Tokesi N, Stieger B, Rushing E, et al.
Front Pharmacol . 2022 Sep; 13:958023. PMID: 36120371
Organic anion transporting polypeptide 3A1 (OATP3A1, encoded by the gene) is a prostaglandin, oligopeptide, and steroid/thyroid hormone transporter with wide tissue distribution, expressed, e.g., in the human brain and testis....
9.
Zeke A, Takacs T, Sok P, Nemeth K, Kirsch K, Egri P, et al.
Nat Commun . 2022 Sep; 13(1):5439. PMID: 36114179
Serine/threonine phosphorylation of insulin receptor substrate (IRS) proteins is well known to modulate insulin signaling. However, the molecular details of this process have mostly been elusive. While exploring the role...
10.
Dobson L, Tusnady G
Int J Mol Sci . 2021 Nov; 22(22). PMID: 34830151
Transmembrane proteins (TMPs) play important roles in cells, ranging from transport processes and cell adhesion to communication. Many of these functions are mediated by intrinsically disordered regions (IDRs), flexible protein...