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Gyorgy Varady

Explore the profile of Gyorgy Varady including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 836
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Recent Articles
1.
Toth O, Racz G, Olah E, Toth M, Szabo E, Varady G, et al.
Sci Rep . 2025 Jan; 15(1):1052. PMID: 39774187
Cell cycle-dependent gene expression analysis is particularly important as numerous genes show tightly regulated expression patterns at different phases of the cell cycle. For cancer cells, analysis of cell cycle-related...
2.
Mozner O, Szabo E, Kulin A, Varady G, Moldvay J, Vass V, et al.
PLoS One . 2025 Jan; 20(1):e0316396. PMID: 39752416
In this study, we analyzed the potential associations of selected laboratory and anamnestic parameters, as well as 12 genetic polymorphisms (SNPs), with clinical COVID-19 occurrence and severity in 869 hospitalized...
3.
Szepesi Kovacs D, Pasztor B, Abranyi-Balogh P, Petri L, Imre T, Simon J, et al.
Bioconjug Chem . 2024 Aug; 35(9):1373-1379. PMID: 39151068
In recent years, antibody conjugates have evolved as state-of-the-art options for diagnostic and therapeutic applications. During site-selective antibody conjugation, incomplete rebridging of antibody chains limits the homogeneity of conjugates and...
4.
Martinek R, Lozsa R, Poti A, Nemeth E, Varady G, Szabo P, et al.
Chemosphere . 2024 Jun; 362:142700. PMID: 38936485
Pesticides are significant environmental pollutants, and many of them possess mutagenic potential, which is closely linked to carcinogenesis. Here we tested the mutagenicity of all six pesticides classified probably carcinogenic...
5.
Vajda F, Szepesi A, Erdei Z, Szabo E, Varady G, Kiss D, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38674102
Mesenchymal stem cells (MSCs) are an integral part of the tumor microenvironment (TME); however, their role is somewhat controversial: conflicting reports suggest that, depending on the stage of tumor development,...
6.
Amin H, Abukhairan R, Szabo B, Jacksi M, Varady G, Lozsa R, et al.
Protein Sci . 2023 Dec; 33(1):e4847. PMID: 38058280
Histone lysine methyltransferases (HKMTs) perform vital roles in cellular life by controlling gene expression programs through the posttranslational modification of histone tails. Since many of them are intimately involved in...
7.
Szepesi Kovacs D, Kontra B, Chiovini B, Muller D, Toth E, Abranyi-Balogh P, et al.
Org Biomol Chem . 2023 Nov; 21(44):8829-8836. PMID: 37917021
An asymmetric cyanine-type fluorescent dye was designed and synthesized a versatile, multi-step process, aiming to conjugate with an Her2+ receptor specific antibody by an azide-alkyne click reaction. The aromaticity and...
8.
Mozner O, Zambo B, Bartos Z, Gergely A, Szabo K, Jezso B, et al.
Membranes (Basel) . 2023 Oct; 13(10). PMID: 37887994
The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this...
9.
Szepesi Kovacs D, Chiovini B, Muller D, Toth E, Fulop A, Abranyi-Balogh P, et al.
ACS Omega . 2023 Jul; 8(25):22836-22843. PMID: 37396252
A novel family of julolidine-containing fluorescent rhodols equipped with a wide variety of substituents was synthesized in a versatile two-step process. The prepared compounds were fully characterized and exhibited excellent...
10.
Racz G, Nagy N, Varady G, Tovari J, Apati A, Vertessy B
Sci Rep . 2023 May; 13(1):7760. PMID: 37173337
In human cells two dUTPase isoforms have been described: one nuclear (DUT-N) and one mitochondrial (DUT-M), with cognate localization signals. In contrast, here we identified two additional isoforms; DUT-3 without...