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G Roma

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Articles 59
Citations 168
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Recent Articles
1.
Oliva A, Curtolo A, Falletta A, Sacco F, Lancellotti F, Carnevalini M, et al.
Int J Antimicrob Agents . 2024 Nov; 64(6):107365. PMID: 39490539
Background: Fosfomycin (FOS) is gaining increasing importance as part of combination therapy for the treatment of carbapenem-resistant Acinetobacter baumannii (CRAB) and KPC-producing Klebsiella pneumoniae (KPC-Kp), thanks to its in vitro...
2.
Martin-Samos L, Roma G, Rinke P, Limoge Y
Phys Rev Lett . 2010 Apr; 104(7):075502. PMID: 20366896
The long-standing problem of the oxygen self-diffusion mechanism in silicon dioxide, a prototypical oxide, both in the crystalline and in the amorphous phase, is studied from first principles. We demonstrate...
3.
Gatta E, Cupello A, Di Braccio M, Grossi G, Ferruzzi R, Roma G, et al.
Neuroscience . 2010 Jan; 166(3):917-23. PMID: 20096335
Various new 1,5-benzodiazepine compounds were synthesized and tested for their biological activity in terms of effects on GABA(A) receptors of rat cerebellar granules in culture. Their effects were compared to...
4.
Sardiello M, Annunziata I, Roma G, Ballabio A
Hum Mol Genet . 2005 Sep; 14(21):3203-17. PMID: 16174644
Sulfatases catalyze the hydrolysis of sulfate ester bonds from a wide variety of substrates. Several human inherited diseases are caused by the deficiency of individual sulfatases, while in patients with...
5.
Di Braccio M, Grossi G, Roma G, Vargiu L, Mura M, Marongiu M
Eur J Med Chem . 2002 Jan; 36(11-12):935-49. PMID: 11755236
A number of properly substituted 5H-pyrimido[4,5-b][1,5]benzodiazepines (2) and pyrazolo[3,4-b][1,5]benzodiazepines (3 and 4), as well as compounds 5-7, which are derivatives of new tetracyclic systems, were prepared as nevirapine analogues through...
6.
Fruscella P, Sottocorno M, Di Braccio M, Diomede L, Piccardi N, Cagnotto A, et al.
Pharmacol Res . 2001 Jun; 43(5):445-52. PMID: 11394936
The 1,4- and the 1,5-benzodiazepines (BDZ) are commonly used as anxiolytic and anticonvulsive drugs. It has been suggested that they influence, particularly through stimulation of peripheral BDZ receptors, some immune...
7.
Roma G, Limoge Y, Baroni S
Phys Rev Lett . 2001 Jun; 86(20):4564-7. PMID: 11384284
We have studied the formation energy of the simplest oxygen defects in alpha-quartz, the oxygen vacancy and interstitial, by an ab initio approach based on density functional theory in the...
8.
Roma G, Di Braccio M, Grossi G, Mattioli F, Ghia M
Eur J Med Chem . 2001 Jan; 35(11):1021-35. PMID: 11137230
The title compounds (8) were synthesized through the cyclocondensation of the corresponding N-substituted 4-amino-2-chloro-1,8-naphthyridine-3-carboxamides (4) with the proper hydrazides, in order to evaluate their anti-inflammatory and anti-aggressive properties. Several compounds...
9.
Roma G, Cinone N, Di Braccio M, Grossi G, Leoncini G, Signorello M, et al.
Bioorg Med Chem . 2000 May; 8(4):751-68. PMID: 10819164
2-(1-Piperazinyl)-4H-pyrido[1,2-a]pyrimidin-4-one (5a) is a recently described in vitro inhibitor of human platelet aggregation which specifically inhibits the activity of high affinity cAMP phosphodiesterase. A number of substitution derivatives, isosteres, and...
10.
Borassi A, Carnasciali M, Mugnoli A, Roma G
Acta Crystallogr C . 2000 Apr; 56 ( Pt 2):258-9. PMID: 10777910
No abstract available.