G L Stiles
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Explore the profile of G L Stiles including associated specialties, affiliations and a list of published articles.
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115
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2470
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Recent Articles
21.
Ren H, Stiles G
Mol Pharmacol
. 1995 Dec;
48(6):975-80.
PMID: 8848013
There are two types of transcripts for the human A1, adenosine receptor. They are expressed in a tissue-specific manner in human tissues and contain distinct exons. Previously, it had appeared...
22.
Palmer T, Poucher S, Jacobson K, Stiles G
Mol Pharmacol
. 1995 Dec;
48(6):970-4.
PMID: 8848012
The A2a adenosine receptor (AR) mediates several important physiological effects of adenosine, including vasodilation and inhibition of platelet aggregation. Until recently, no antagonist radioligand of sufficient selectivity or affinity was...
23.
24.
Deckert J, Nothen M, Bryant S, Ren H, Wolf H, Stiles G, et al.
Biochem Biophys Res Commun
. 1995 Sep;
214(2):614-21.
PMID: 7677773
Adenosine is a major inhibitory neuromodulator in the central nervous system. One of the receptors mediating the central effects of adenosine is the adenosine A1 receptor. We performed a systematic...
25.
Differential interaction with and regulation of multiple G-proteins by the rat A3 adenosine receptor
Palmer T, Gettys T, Stiles G
J Biol Chem
. 1995 Jul;
270(28):16895-902.
PMID: 7622506
Interaction of the rat A3 adenosine receptor (A3AR) with G-proteins has been assessed using a stably transfected Chinese hamster ovary cell system. The non-selective AR agonist 5'-N-ethylcarboxamidoadenosine (NECA) increased the...
26.
27.
Jacobson K, Siddiqi S, Olah M, Ji X, Melman N, Bellamkonda K, et al.
J Med Chem
. 1995 May;
38(10):1720-35.
PMID: 7752196
9-Alkyladenine derivatives and ribose-modified N6-benzyladenosine derivatives were synthesized in an effort to identify selective ligands for the rat A3 adenosine receptor and leads for the development of antagonists. The derivatives...
28.
Olah M, Ren H, Stiles G
Arch Int Pharmacodyn Ther
. 1995 Jan;
329(1):135-50.
PMID: 7639615
Adenosine produces a wide variety of effects throughout the body via activation of cell surface adenosine receptors. Adenosine receptors belong to the family of seven transmembrane domain G protein-coupled receptors...
29.
Olah M, Stiles G
Annu Rev Pharmacol Toxicol
. 1995 Jan;
35:581-606.
PMID: 7598508
Adenosine receptors (ARs) are members of the G protein-coupled receptor family and mediate the multiple physiological effects of adenosine. Currently, four AR subtypes have been cloned: A1AR, A2aAR, A2bAR, and...
30.
Kim H, Ji X, Melman N, Olah M, Stiles G, Jacobson K
J Med Chem
. 1994 Nov;
37(23):4020-30.
PMID: 7966162
1,3-Dibutylxanthine 7-riboside has been found to be a partial agonist at A3 adenosine receptors (van Galen et al. Mol. Pharmacol. 1994, 45, 1101-1111). 1,3-Dialkylxanthine 7-riboside analogues modified at the 1-,...