G K Whitfield
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Explore the profile of G K Whitfield including associated specialties, affiliations and a list of published articles.
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34
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1205
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Recent Articles
1.
Jurutka P, Whitfield G, Hsieh J, Thompson P, Haussler C, Haussler M
Rev Endocr Metab Disord
. 2001 Nov;
2(2):203-16.
PMID: 11705326
No abstract available.
2.
Thompson P, Remus L, Hsieh J, Jurutka P, Whitfield G, Galligan M, et al.
J Mol Endocrinol
. 2001 Sep;
27(2):211-27.
PMID: 11564604
The vitamin D receptor (VDR) stimulates transcription as a 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3))-activated heterodimer with retinoid X receptor (RXR). RXR also forms homodimers to mediate 9-cis retinoic acid (9-cis RA)-induced gene...
3.
Whitfield G, Remus L, Jurutka P, Zitzer H, Oza A, Dang H, et al.
Mol Cell Endocrinol
. 2001 May;
177(1-2):145-59.
PMID: 11377830
The functional significance of two unlinked human vitamin D receptor (hVDR) gene polymorphisms was evaluated in twenty human fibroblast cell lines. Genotypes at both a Fok I restriction site (F/f)...
4.
Jurutka P, Remus L, Whitfield G, Thompson P, Hsieh J, Zitzer H, et al.
Mol Endocrinol
. 2000 Mar;
14(3):401-20.
PMID: 10707958
The human vitamin D receptor (hVDR) is a ligand-regulated transcription factor that mediates the actions of the 1,25-dihydroxyvitamin D3 hormone to effect bone mineral homeostasis. Employing mutational analysis, we characterized...
5.
Jurutka P, Remus L, Whitfield G, Galligan M, Haussler C, Haussler M
Biochem Biophys Res Commun
. 2000 Feb;
267(3):813-9.
PMID: 10673374
Human vitamin D receptor (hVDR) fused to glutathione S-transferase was utilized to detect a VDR-interacting protein (VIP) of approximately 170 kDa. VIP(170) is expressed in osteoblast-like ROS 17/2.8 cells and,...
6.
Whitfield G, Jurutka P, Haussler C, Haussler M
J Cell Biochem
. 2000 Jan;
Suppl 32-33:110-22.
PMID: 10629110
The characterization of the superfamily of nuclear receptors, in particular the steroid/retinoid/thyroid hormone receptors, has resulted in a more complete understanding of how a repertoire of hormonally and nutritionally derived...
7.
Hsieh J, Whitfield G, Oza A, Dang H, Price J, Galligan M, et al.
Biochemistry
. 1999 Dec;
38(49):16347-58.
PMID: 10587460
The vitamin D receptor (VDR) binds 1,25-dihydroxyvitamin D(3) and mediates its actions on gene transcription by heterodimerizing with retinoid X receptors (RXRs) on direct repeat (DR+3) vitamin D responsive elements...
8.
Thompson P, Hsieh J, Whitfield G, Haussler C, Jurutka P, Galligan M, et al.
J Cell Biochem
. 1999 Oct;
75(3):462-80.
PMID: 10536369
The vitamin D receptor (VDR) is a transcription factor believed to function as a heterodimer with the retinoid X receptor (RXR). However, it was reported [Schräder et al., 1994] that,...
9.
Chen S, Wu J, Hsieh J, Whitfield G, Jurutka P, Haussler M, et al.
Hypertension
. 1998 Jun;
31(6):1338-42.
PMID: 9622151
We showed previously that liganded vitamin D receptor (VDR) effects a suppression of human atrial natriuretic peptide (hANP) gene-promoter activity in cultured neonatal rat atrial myocytes. In the present study,...
10.
Thompson P, Jurutka P, Haussler C, Whitfield G, Haussler M
J Biol Chem
. 1998 May;
273(14):8483-91.
PMID: 9525962
Gel mobility shift analysis was utilized to investigate the molecular function of 1alpha,25-dihydroxyvitamin D3 (1,25-(OH)2D3) and 9-cis-retinoic acid (9-cis-RA) ligands in the binding of the vitamin D receptor (VDR) and...