G Denecker
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Explore the profile of G Denecker including associated specialties, affiliations and a list of published articles.
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25
Citations
1577
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0
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Recent Articles
11.
Cornelis G, Denecker G
Nat Med
. 2001 Jan;
7(1):21-3.
PMID: 11135606
Little is known about the mechanism by which Yops, proteins that Yersinia inject into the cytosol of macrophage, cause downregulation of the inflammatory response and diseases such as the plague....
12.
Daemen M, Heemskerk V, Vant Veer C, Denecker G, Wolfs T, Vandenabeele P, et al.
Circulation
. 2000 Sep;
102(12):1420-6.
PMID: 10993862
Background: Ischemia followed by reperfusion (I/R) causes apoptosis, inflammation, and tissue damage leading to organ malfunction. Ischemic preconditioning can protect against such injury. This study investigates the contribution of the...
13.
Cornelis S, Bruynooghe Y, Denecker G, Van Huffel S, Tinton S, Beyaert R
Mol Cell
. 2000 Jul;
5(4):597-605.
PMID: 10882096
PITSLRE protein kinases are related to the large family of cyclin-dependent kinases. They have been proposed to act as tumor suppressor genes and have been shown to play a role...
14.
Penning L, Denecker G, Vercammen D, Declercq W, Schipper R, Vandenabeele P
Cytokine
. 2000 Jun;
12(6):747-50.
PMID: 10843757
Rat/mouse T cell hybridoma-derived PC60 R55/R75 cells were used as a model to study the role of intracellular potassium in TNF-induced apoptosis and gene induction. A reduction of intracellular potassium...
15.
Heyninck K, Denecker G, De Valck D, Fiers W, Beyaert R
Anticancer Res
. 2000 Feb;
19(4B):2863-8.
PMID: 10652565
Tumor Necrosis Factor (TNF) is a cytokine that induces necrotic and apoptotic forms of cell death. The TNF-induced signalling mechanisms leading to necrosis or apoptosis are partially distinct, and are...
16.
Denecker G, Dooms H, van Loo G, Vercammen D, Grooten J, Fiers W, et al.
FEBS Lett
. 2000 Jan;
465(1):47-52.
PMID: 10620704
Time kinetics of phosphatidyl serine (PS) exposure were compared to other apoptotic parameters following different apoptotic stimuli. Our data indicate that anti-Fas treatment of L929sAhFas cells results in rapid exposure...
17.
Van Molle W, Denecker G, Rodriguez I, Brouckaert P, Vandenabeele P, Libert C
J Immunol
. 1999 Nov;
163(10):5235-41.
PMID: 10553044
Lethal hepatitis can be induced by an agonistic anti-Fas Ab in normal mice or by TNF in mice sensitized to d -(+)-galactosamine or actinomycin D. In all three models, we...
18.
Daemen M, van t Veer C, Denecker G, Heemskerk V, Wolfs T, Clauss M, et al.
J Clin Invest
. 1999 Sep;
104(5):541-9.
PMID: 10487768
Ischemia followed by reperfusion leads to severe organ injury and dysfunction. Inflammation is considered to be the most important cause of tissue injury in organs subjected to ischemia. The mechanism...
19.
Vercammen D, Brouckaert G, Denecker G, van de Craen M, Declercq W, Fiers W, et al.
J Exp Med
. 1998 Sep;
188(5):919-30.
PMID: 9730893
Murine L929 fibrosarcoma cells were transfected with the human Fas (APO-1/CD95) receptor, and the role of various caspases in Fas-mediated cell death was assessed. Proteolytic activation of procaspase-3 and -7...
20.
Declercq W, Denecker G, Fiers W, Vandenabeele P
J Immunol
. 1998 Jul;
161(1):390-9.
PMID: 9647248
TNF-R55 is the main receptor mediating TNF-induced cytotoxicity. However, in some cells TNF-R75 also signals cell death. In PC60 cells, the presence of both receptor types is required to induce...