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G Denecker

Explore the profile of G Denecker including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 1577
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Recent Articles
1.
Denecker G, Vandamme N, Akay O, Koludrovic D, Taminau J, Lemeire K, et al.
Cell Death Differ . 2014 Apr; 21(8):1250-61. PMID: 24769727
Deregulation of signaling pathways that control differentiation, expansion and migration of neural crest-derived melanoblasts during normal development contributes also to melanoma progression and metastasis. Although several epithelial-to-mesenchymal (EMT) transcription factors,...
2.
De Craene B, Denecker G, Vermassen P, Taminau J, Mauch C, Derore A, et al.
Cell Death Differ . 2013 Oct; 21(2):310-20. PMID: 24162662
Expression of the EMT-inducing transcription factor Snail is enhanced in different human cancers. To investigate the in vivo role of Snail during progression of epithelial cancer, we used a mouse...
3.
Lambertz I, Nittner D, Mestdagh P, Denecker G, Vandesompele J, Dyer M, et al.
Cell Death Differ . 2009 Dec; 17(4):633-41. PMID: 20019750
Human tumors are characterized by widespread reduction in microRNA (miRNA) expression, although it is unclear how such changes come about and whether they have an etiological role in the disease....
4.
Krysko D, Denecker G, Festjens N, Gabriels S, Parthoens E, DHerde K, et al.
Cell Death Differ . 2006 Apr; 13(12):2011-22. PMID: 16628234
The present study characterized two different internalization mechanisms used by macrophages to engulf apoptotic and necrotic cells. Our in vitro phagocytosis assay used a mouse macrophage cell line, and murine...
5.
Lippens S, Denecker G, Ovaere P, Vandenabeele P, Declercq W
Cell Death Differ . 2005 Oct; 12 Suppl 2:1497-508. PMID: 16247497
Homeostasis implies a balance between cell growth and cell death. This balance is essential for the development and maintenance of multicellular organisms. Homeostasis is controlled by several mechanisms including apoptosis,...
6.
Vantieghem A, Xu Y, Declercq W, Vandenabeele P, Denecker G, Vandenheede J, et al.
Photochem Photobiol . 2001 Sep; 74(2):133-42. PMID: 11547546
In this study we show that overexpression of Bcl-2 in PC60R1R2 cells reveals a caspase-dependent mechanism of cytochrome c release following photodynamic therapy (PDT) with hypericin. Bcl-2 overexpression remarkably delayed...
7.
Denecker G, Vercammen D, Steemans M, Vanden Berghe T, Brouckaert G, van Loo G, et al.
Cell Death Differ . 2001 Aug; 8(8):829-40. PMID: 11526436
In L929sAhFas cells, tumor necrosis factor (TNF) leads to necrotic cell death, whereas agonistic anti-Fas antibodies elicit apoptotic cell death. Apoptosis, but not necrosis, is correlated with a rapid externalization...
8.
Daemen M, Denecker G, Vant Veer C, Wolfs T, Vandenabeele P, Buurman W
Transplantation . 2001 May; 71(6):778-84. PMID: 11330542
Background: Upon transplantation, donor organs subjected to prolonged ischemia suffer from reperfusion injury. Recent observations suggest that caspase activation is involved in inducing the deleterious inflammatory reaction that mediates reperfusion...
9.
Denecker G, Vercammen D, Declercq W, Vandenabeele P
Cell Mol Life Sci . 2001 Apr; 58(3):356-70. PMID: 11315185
Apoptosis and necrosis are two distinct forms of cell death. Caspases are indispensable as initiators and effectors of apoptotic cell death and are involved in many of the morphological and...
10.
Denecker G, Declercq W, Geuijen C, Boland A, Benabdillah R, van Gurp M, et al.
J Biol Chem . 2001 Mar; 276(23):19706-14. PMID: 11279213
Yersinia enterocolitica induces apoptosis in macrophages by injecting the plasmid-encoded YopP (YopJ in other Yersinia species). Recently it was reported that YopP/J is a member of an ubiquitin-like protein cysteine...