G A Rutter
Overview
Explore the profile of G A Rutter including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
82
Citations
2932
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Suba K, Patel Y, Martin-Alonso A, Hansen B, Xu X, Roberts A, et al.
Mol Metab
. 2024 Apr;
85:101947.
PMID: 38677509
Objective: Type 2 diabetes (T2D) is characterised by the loss of first-phase insulin secretion. We studied mice with β-cell selective loss of the glucagon receptor (Gcgr X Ins-1), to investigate...
2.
Laurent D, Vinet L, Lamprianou S, Daval M, Filhoulaud G, Ktorza A, et al.
Diabetes Obes Metab
. 2015 Aug;
18(1):6-15.
PMID: 26228188
Diabetes mellitus is a growing worldwide epidemic disease, currently affecting 1 in 12 adults. Treatment of disease complications typically consumes ∼10% of healthcare budgets in developed societies. Whilst immune-mediated destruction...
3.
Broichhagen J, Frank J, Johnston N, Mitchell R, Smid K, Marchetti P, et al.
Chem Commun (Camb)
. 2015 Mar;
51(27):6018-21.
PMID: 25744824
Azobenzene photoresponsive elements can be installed on sulfonylureas, yielding optical control over pancreatic beta cell function and insulin release. An obstacle to such photopharmacological approaches remains the use of ultraviolet-blue...
4.
Pancholi J, Hodson D, Jobe K, Rutter G, Goldup S, Watkinson M
Chem Sci
. 2015 Jan;
5(9):3528-3535.
PMID: 25580213
We describe a one-pot strategy for the high yielding, operationally simple synthesis of fluorescent probes for Zn that bear biological targeting groups and exemplify the utility of our method through...
5.
Rutter G
Diabet Med
. 2014 Sep;
31(12):1480-7.
PMID: 25186316
Whilst the heritable nature of Type 2 diabetes has been recognized for many years, only in the past two decades have linkage analyses in families and genome-wide association studies in...
6.
Locke J, da Silva Xavier G, Dawe H, Rutter G, Harries L
Diabetologia
. 2013 Oct;
57(1):122-8.
PMID: 24149837
Aims/hypothesis: Type 2 diabetes is characterised by progressive beta cell dysfunction, with changes in gene expression playing a crucial role in its development. MicroRNAs (miRNAs) are post-transcriptional regulators of gene...
7.
Pullen T, Rutter G
Diabetes Obes Metab
. 2012 Nov;
15(6):503-12.
PMID: 23121289
Outside of the biological arena the term 'repression' often has a negative connotation. However, in the pancreatic β-cell a small group of genes, which are abundantly expressed in most if...
8.
da Silva Xavier G, Mondragon A, Sun G, Chen L, McGinty J, French P, et al.
Diabetologia
. 2012 Jun;
55(10):2667-2676.
PMID: 22717537
Aims/hypothesis: Individuals carrying type 2 diabetes risk alleles in TCF7L2 display decreased beta cell levels of T cell factor 7 like-2 (TCF7L2) immunoreactivity, and impaired insulin secretion and beta cell...
9.
Locke J, da Silva Xavier G, Rutter G, Harries L
Diabetologia
. 2011 Sep;
54(12):3078-82.
PMID: 21913056
Aims/hypothesis: Intronic single nucleotide polymorphisms within the transcription factor 7-like 2 (TCF7L2) gene are associated with risk of type 2 diabetes. It is widely hypothesised that the predisposing variation is...
10.
da Silva Xavier G, Farhan H, Kim H, Caxaria S, Johnson P, Hughes S, et al.
Diabetologia
. 2010 Dec;
54(4):819-27.
PMID: 21181396
Aims/hypothesis: We assessed whether per-arnt-sim (PAS) domain-containing protein kinase (PASK) is involved in the regulation of glucagon secretion. Methods: mRNA levels were measured in islets by quantitative PCR and in...