G A Rathbun
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Explore the profile of G A Rathbun including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
874
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Recent Articles
1.
ONeill T, Dwyer A, Ziv Y, Chan D, Lees-Miller S, Abraham R, et al.
J Biol Chem
. 2000 May;
275(30):22719-27.
PMID: 10801797
The ataxia telangiectasia mutated (ATM) gene encodes a serine/threonine protein kinase that plays a critical role in genomic surveillance and development. Here, we use a peptide library approach to define...
2.
Borghesani P, Alt F, Bottaro A, Davidson L, Aksoy S, Rathbun G, et al.
Proc Natl Acad Sci U S A
. 2000 Mar;
97(7):3336-41.
PMID: 10716718
Motor incoordination, immune deficiencies, and an increased risk of cancer are the characteristic features of the hereditary disease ataxia-telangiectasia (A-T), which is caused by mutations in the ATM gene. Through...
3.
Rathbun G, Ziv Y, Lai J, Hill D, Abraham R, Shiloh Y, et al.
Curr Top Microbiol Immunol
. 1999 Jul;
246:267-73; discussion 274.
PMID: 10396065
No abstract available.
4.
Gao Y, Sun Y, Frank K, Dikkes P, Fujiwara Y, Seidl K, et al.
Cell
. 1999 Jan;
95(7):891-902.
PMID: 9875844
XRCC4 was identified via a complementation cloning method that employed an ionizing radiation (IR)-sensitive hamster cell line. By gene-targeted mutation, we show that XRCC4 deficiency in primary murine cells causes...
5.
Frank K, Sekiguchi J, Seidl K, Swat W, Rathbun G, Cheng H, et al.
Nature
. 1998 Nov;
396(6707):173-7.
PMID: 9823897
The DNA-end-joining reactions used for repair of double-strand breaks in DNA and for V(D)J recombination, the process by which immunoglobulin and T-cell antigen-receptor genes are assembled from multiple gene segments,...
6.
Kirch S, Rathbun G, Oettinger M
EMBO J
. 1998 Aug;
17(16):4881-6.
PMID: 9707447
Immunoglobulin genes are assembled during lymphoid development by a series of site-specific rearrangements that are tightly regulated to ensure that functional antibodies are generated in B (but not T) cells...
7.
Gu Y, Seidl K, Rathbun G, Zhu C, Manis J, Van der Stoep N, et al.
Immunity
. 1997 Dec;
7(5):653-65.
PMID: 9390689
Ku70, Ku80, and DNA-PKcs are subunits of the DNA-dependent protein kinase (DNA-PK), an enzyme implicated in DNA double-stranded break repair and V(D)J recombination. Our Ku70-deficient mice were about 50% the...
8.
Blankenstein T, Rathbun G, Tucker P, Krawinkel U
Mol Immunol
. 1989 Mar;
26(3):319-22.
PMID: 2704376
The peculiar pattern of nucleotide differences between germline VH genes V104A/VAR104 and 122B could be the result of an exchange of genetic information through gene conversion. A palindromic sequence in...
9.
Rathbun G, Otani F, Milner E, Capra J, Tucker P
J Mol Biol
. 1988 Aug;
202(3):383-95.
PMID: 3139886
The nucleotide sequences of the coding as well as the flanking regions of 11 A/J J558 heavy chain variable region (VH) gene segments are presented. Among these J558 VH segments...
10.
Rathbun G, Born W, Kuziel W, Tucker P
Immunogenetics
. 1988 Jan;
27(2):121-6.
PMID: 2891611
We have isolated an unusual T cell receptor gamma chain cDNA clone (gamma 7.1) from a library made from RNA derived from adult thymus of C57BL/Ka mice. This cDNA clone...