K J Seidl
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Explore the profile of K J Seidl including associated specialties, affiliations and a list of published articles.
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10
Citations
810
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Recent Articles
1.
Gartner F, Alt F, MONROE R, Seidl K
J Exp Med
. 2000 Dec;
192(12):1745-54.
PMID: 11120771
Splenic B lineage cells expressing recombination activation genes (RAG(+)) in mice immunized with 4-hydroxy-3-nitrophenyl-acetyl coupled to chicken gamma-globulin (NP-CGG) and the adjuvant aluminum-hydroxide (alum) have been proposed to be mature...
2.
MONROE R, Seidl K, Gaertner F, Han S, Chen F, Sekiguchi J, et al.
Immunity
. 1999 Sep;
11(2):201-12.
PMID: 10485655
We generated mice in which a functional RAG2:GFP fusion gene is knocked in to the endogenous RAG2 locus. In bone marrow and thymus, RAG2:GFP expression occurs in appropriate stages of...
3.
Seidl K, Manis J, Bottaro A, Zhang J, Davidson L, Kisselgof A, et al.
Proc Natl Acad Sci U S A
. 1999 Mar;
96(6):3000-5.
PMID: 10077626
The Ig heavy chain (IgH) constant region (CH) genes are organized from 5' to 3' in the order Cmicro, Cdelta, Cgamma3, Cgamma1, Cgamma2b, Cgamma2a, Cepsilon, and Calpha. Expression of CH...
4.
Seidl K, Wilshire J, Mackenzie J, Kantor A, Herzenberg L
Proc Natl Acad Sci U S A
. 1999 Mar;
96(5):2262-7.
PMID: 10051629
Antibodies to phosphatidylcholine (PtC), a common constituent of mammalian and bacterial cell membranes, represent a large proportion of the natural antibody repertoire in mice. Previous studies of several mouse strains...
5.
Gao Y, Sun Y, Frank K, Dikkes P, Fujiwara Y, Seidl K, et al.
Cell
. 1999 Jan;
95(7):891-902.
PMID: 9875844
XRCC4 was identified via a complementation cloning method that employed an ionizing radiation (IR)-sensitive hamster cell line. By gene-targeted mutation, we show that XRCC4 deficiency in primary murine cells causes...
6.
Seidl K, Bottaro A, Vo A, Zhang J, Davidson L, Alt F
Int Immunol
. 1998 Dec;
10(11):1683-92.
PMID: 9846697
Germline CH transcripts initiate from a promoter upstream of a non-coding I exon, proceed through the switch (S) region and terminate downstream of the associated CH exons. To elucidate the...
7.
Frank K, Sekiguchi J, Seidl K, Swat W, Rathbun G, Cheng H, et al.
Nature
. 1998 Nov;
396(6707):173-7.
PMID: 9823897
The DNA-end-joining reactions used for repair of double-strand breaks in DNA and for V(D)J recombination, the process by which immunoglobulin and T-cell antigen-receptor genes are assembled from multiple gene segments,...
8.
Gu Y, Seidl K, Rathbun G, Zhu C, Manis J, Van der Stoep N, et al.
Immunity
. 1997 Dec;
7(5):653-65.
PMID: 9390689
Ku70, Ku80, and DNA-PKcs are subunits of the DNA-dependent protein kinase (DNA-PK), an enzyme implicated in DNA double-stranded break repair and V(D)J recombination. Our Ku70-deficient mice were about 50% the...
9.
Seidl K, Mackenzie J, Wang D, Kantor A, KABAT E, Herzenberg L
Int Immunol
. 1997 May;
9(5):689-702.
PMID: 9184914
Single-cell PCR analyses of expressed Ig H and L chain sequences presented here show that certain rearrangements occur repeatedly and account for a major segment of the well-studied repertoire of...
10.
Seidl K, Mackenzie J, Wang D, Kantor A, KABAT E, Herzenberg L
Ann N Y Acad Sci
. 1997 Apr;
815:484-8.
PMID: 9186705
No abstract available.