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Fuqu Yu

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Articles 13
Citations 351
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Recent Articles
1.
Cowden J, Yu F, Banie H, Farahani M, Ling P, Nguyen S, et al.
Ann Rheum Dis . 2013 Oct; 73(3):600-8. PMID: 24126456
Objective: The histamine H4 receptor (H4R) has been shown to drive inflammatory responses in models of asthma, colitis and dermatitis, and in these models it appears to affect both innate...
2.
Cowden J, Yu F, Challapalli M, Huang J, Kim S, Fung-Leung W, et al.
Inflamm Res . 2013 Mar; 62(6):599-607. PMID: 23532396
Objective: Antagonism of the histamine H4 receptor (H4R) has been shown to be anti-inflammatory in a number of preclinical disease models, however the exact mechanisms behind this are still being...
3.
Yu F, Al-Shyoukh I, Feng J, Li X, Liao C, Ho C, et al.
PLoS One . 2011 Sep; 6(6):e20998. PMID: 21904595
The ability to control cellular functions can bring about many developments in basic biological research and its applications. The presence of multiple signals, internal as well as externally imposed, introduces...
4.
Al-Shyoukh I, Yu F, Feng J, Yan K, Dubinett S, Ho C, et al.
BMC Syst Biol . 2011 Jun; 5:88. PMID: 21624115
Background: Cells constantly sense many internal and environmental signals and respond through their complex signaling network, leading to particular biological outcomes. However, a systematic characterization and optimization of multi-signal responses...
5.
Yu F, Bonaventure P, Thurmond R
Adv Exp Med Biol . 2011 May; 709:125-40. PMID: 21618893
The field of histamine research has progressed far from a century ago when the first biological functions of histamine were identified. It is now known that histamine function is mediated...
6.
Rao N, Riley J, Banie H, Xue X, Sun B, Crawford S, et al.
Am J Respir Crit Care Med . 2010 Jan; 181(9):899-907. PMID: 20110560
Rationale: Allergic asthma is characterized by reversible airway obstruction, lung inflammation, and airway hyperresponsiveness (AHR). Previous studies using leukotriene B(4) (LTB(4)) receptor 1-deficient mice and adoptive transfer experiments have suggested...
7.
Sun C, Usui T, Yu F, Al-Shyoukh I, Shamma J, Sun R, et al.
Integr Biol (Camb) . 2009 Oct; 1(1):123-30. PMID: 19851479
Cells serve as basic units of life and represent intricate biological molecular systems. The vast number of cellular molecules with their signaling and regulatory circuitries forms an intertwined network. In...
8.
Lee S, Deng H, Yu F, Melega W, Damoiseaux R, Bradley K, et al.
J Acquir Immune Defic Syndr . 2008 Jul; 48(5):531-40. PMID: 18645521
Background: Kaposi's sarcoma-associated herpesvirus (KSHV) possesses two distinct life cycles, lytic replication and latency. An immediate early viral protein, Replication and transcription activator (RTA), is responsible for the virus switch...
9.
Cho H, Yu F, Sun R, Lee D, Song M
Arch Virol . 2008 Jul; 153(8):1517-25. PMID: 18607675
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to Kaposi's sarcoma primary effusion lymphoma (PEL), and multicentric Castleman's disease. Intentional lytic induction of gammaherpesviruses in the presence of antiviral drugs is...
10.
Wong P, Yu F, Shahangian A, Cheng G, Sun R, Ho C
Proc Natl Acad Sci U S A . 2008 Mar; 105(13):5105-10. PMID: 18356295
A mixture of drugs is often more effective than using a single effector. However, it is extremely challenging to identify potent drug combinations by trial and error because of the...