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Fuchao Yu

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Articles 36
Citations 92
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Recent Articles
1.
Zhen P, Jiang Q, Yu F, Xu X, Wei Q, Liu X, et al.
J Control Release . 2025 Jan; 379:609-620. PMID: 39842726
Treatment of myocardial ischemia-reperfusion (MI/R) injury still faces the lack of clinically approved drugs. Apelin-13 is a highly promising drug candidate of MI/R injury, but hampered by its extremely short...
2.
Zhang Z, Xu Y, Peng M, Song S, Wei Y, Hu H, et al.
Chem Commun (Camb) . 2024 Nov; 60(100):14968-14971. PMID: 39605135
A practical, effective, and regioselective palladium-catalyzed ring opening/[4+2] annulation of enaminones with cyclopropenones for the controllable synthesis of highly substituted γ-butenolides and γ-lactams has been described. This method for the...
3.
Peng M, Xie Y, Song S, Zhang Z, Wei Y, Hu H, et al.
Int J Mol Sci . 2024 Nov; 25(22). PMID: 39596141
Commercial DCE is excavated as both a "Cl" source and a solvent for the vinyl C(sp)-H chlorination. The strategy involves a metal-free NBS-mediated C(sp)-H chlorination of enaminones, and affords diverse,...
4.
Yu F, Fang X, Zhu J, Li B, Du B
Am J Transl Res . 2024 Nov; 16(10):5692-5699. PMID: 39544813
Objective: To investigate the prognostic value of interleukin (IL)-10 and glial fibrillary acidic protein (GFPA) in patients with brain glioma following surgery. Methods: The clinical data of 75 patients with...
5.
Yu F, Zhou F, Hao Q, Cao W, Xie L, Xu X, et al.
Sci Rep . 2024 Oct; 14(1):25905. PMID: 39472645
There is a significant interrelationship between cardiovascular disease and obstructive sleep apnea (OSA), as they share common risk factors and comorbidities. This study aimed to investigate the knowledge, attitude, and...
6.
Li B, Yu F, Chen W, Seidel D
Org Lett . 2024 Jul; 26(28):5972-5977. PMID: 38968591
Unprotected alicyclic amines undergo α-C-H bond phosphonylation via a two-stage one-pot process involving the oxidation of amine-derived lithium amides with simple ketone oxidants, generating transient imines which are then captured...
7.
Song S, Peng M, Zhang Z, Hu H, Wei Y, Yan S, et al.
Org Lett . 2024 Jun; 26(23):4980-4985. PMID: 38832696
An unprecedented selective chromone annulation reaction controlled by solvent for the divergent synthesis of two types of 2,3-disubstituted chromone skeletons has been developed. A variety of 2-chromonyl-3-hydrazono-chromones and 2-alkoxy-3-hydrazono-chromones were...
8.
Xie Y, Zhang Z, Zhang B, He N, Peng M, Song S, et al.
J Org Chem . 2024 Jun; 89(12):8521-8530. PMID: 38828704
An oxidative free-radical C(sp)-H bond chlorination strategy of enaminones has been developed by using LiCl as a chlorinating reagent and KSO as an oxidant. This transformation provides a new and...
9.
Zhang Z, Sun H, Zhang M, Song S, Peng M, Dai W, et al.
Org Lett . 2024 May; 26(20):4205-4211. PMID: 38743606
An unprecedented base-controlled selective skeletal rearrangement reaction of hexahydro-4-indol-4-ones has been developed. In this protocol, highly functionalized dihydroxy-4-cyclopenta[]pyridin-4-ones and 8-alkenyl oxepane-2,6-diones were prepared with a broad substrate scope and high...
10.
Xu X, Li S, Wang T, Zhen P, Wei Q, Yu F, et al.
Phytomedicine . 2024 Apr; 128:155390. PMID: 38569296
Background: Well-defined and effective pharmacological interventions for clinical management of myocardial ischemia/reperfusion (MI/R) injury are currently unavailable. Shexiang Baoxin Pill (SBP), a traditional Chinese medicine Previous research on SBP has...