Longkun Chen
Overview
Explore the profile of Longkun Chen including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
266
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0
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Recent Articles
1.
Chen L, Zhang M, Liu M, Liu Z, Qiu Y, Zhang Z, et al.
Chem Commun (Camb)
. 2023 Dec;
60(4):432-435.
PMID: 38086626
An efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as a single coupling partner was demonstrated, in which fused benzodiazepine skeletons were obtained in excellent yields. This...
2.
Zhang M, Chen L, Sun H, Liu Z, Huang J, Yu F
Org Lett
. 2023 Oct;
25(40):7298-7303.
PMID: 37787679
An unprecedented protocol for a Rh(III)-catalyzed [3 + 2] annulation from simple and readily available enaminones and iodonium ylides has been developed. The novel strategy allows for access to a...
3.
Zhang M, Chen L, Sun H, Liu Z, Yan S, Yu F
Org Lett
. 2023 Sep;
25(39):7214-7219.
PMID: 37751319
A novel Rh(III)-catalyzed cascade alkenyl C-H activation/[3 + 2] annulation/pinacol rearrangement reaction of enaminones with iodonium ylides has been developed. This methodology provides a new and straightforward synthetic strategy to...
4.
Sun Y, Liu Z, Liu D, Zhang M, Chen L, Chai Z, et al.
J Org Chem
. 2023 Aug;
88(16):11627-11636.
PMID: 37556793
Syntheses of highly functionalized 4-alkylated 1,4-dihydropyridines (1,4-DHPs) from cyclic ethers and enaminones via iron(II)-mediated oxidative free radical cascade C(sp)-H bond functionalization/C(sp)-O bond cleavage/cyclization reaction have been first developed. This novel...
5.
Liu Z, Sun Y, Zhang M, Chen L, Chen X, Li X, et al.
Org Biomol Chem
. 2023 Jun;
21(26):5475-5480.
PMID: 37341640
An Fe-mediated four-component reaction of enaminones, anhydrides and tetrahydrofuran through a cascade [1 + 2 + 3]-cyclization/esterification process is presented. This protocol provides a new and effective method to construct...
6.
Liu D, Song S, Chen L, Zhang M, Liu Z, Lu X, et al.
Org Biomol Chem
. 2023 Mar;
21(12):2596-2602.
PMID: 36891944
A metal-free regioselective oxidative annulation reaction of readily available 2,4-pentanediones with primary amines has been described. This protocol provides a divergent strategy for the incorporation of various radical donors into...
7.
Sun Y, Chai Z, Liu D, Zhang M, Chen L, Liu Z, et al.
Chemistry
. 2023 Feb;
29(28):e202300297.
PMID: 36825432
Using benzylamines as the C4 source of 1,4-dihydropyridines (1,4-DHPs), a Cu-catalyzed oxidative [1+2+1+2] cascade cyclization for the synthesis of 1,4-DHPs was firstly developed. A broad range of easily available N,N-dimethyl...
8.
Zhang W, Li Y, Jiang D, Xie S, Zeng M, Chen J, et al.
ACS Biomater Sci Eng
. 2021 Jan;
4(6):2067-2080.
PMID: 33445278
The use of synthetic surgical meshes for abdominal hernia repair presents numerous challenges due to insufficient mechanical strength, nonabsorbability, and implant rigidity that leads to complications including chronic inflammatory reactions...
9.
Zhang W, Chen L, Chen J, Wang L, Gui X, Ran J, et al.
Adv Healthc Mater
. 2017 Mar;
6(10).
PMID: 28337854
Due to its excellent biological and mechanical properties, silk fibroin has been intensively explored for tissue engineering and regenerative medicine applications. However, lack of translational evidence has hampered its clinical...
10.
Shen W, Chen J, Zhu T, Chen L, Zhang W, Fang Z, et al.
Stem Cells Transl Med
. 2014 Jan;
3(3):387-94.
PMID: 24448516
Meniscus injury is frequently encountered in clinical practice. Current surgical therapy involving partial or complete meniscectomy relieves pain in the short-term but often leads to osteoarthritis (OA) in the long-term....