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Zhilai Zhang

Explore the profile of Zhilai Zhang including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Zhang Z, Xu Y, Peng M, Song S, Wei Y, Hu H, et al.
Chem Commun (Camb) . 2024 Nov; 60(100):14968-14971. PMID: 39605135
A practical, effective, and regioselective palladium-catalyzed ring opening/[4+2] annulation of enaminones with cyclopropenones for the controllable synthesis of highly substituted γ-butenolides and γ-lactams has been described. This method for the...
2.
Peng M, Xie Y, Song S, Zhang Z, Wei Y, Hu H, et al.
Int J Mol Sci . 2024 Nov; 25(22). PMID: 39596141
Commercial DCE is excavated as both a "Cl" source and a solvent for the vinyl C(sp)-H chlorination. The strategy involves a metal-free NBS-mediated C(sp)-H chlorination of enaminones, and affords diverse,...
3.
Song S, Peng M, Zhang Z, Hu H, Wei Y, Yan S, et al.
Org Lett . 2024 Jun; 26(23):4980-4985. PMID: 38832696
An unprecedented selective chromone annulation reaction controlled by solvent for the divergent synthesis of two types of 2,3-disubstituted chromone skeletons has been developed. A variety of 2-chromonyl-3-hydrazono-chromones and 2-alkoxy-3-hydrazono-chromones were...
4.
Xie Y, Zhang Z, Zhang B, He N, Peng M, Song S, et al.
J Org Chem . 2024 Jun; 89(12):8521-8530. PMID: 38828704
An oxidative free-radical C(sp)-H bond chlorination strategy of enaminones has been developed by using LiCl as a chlorinating reagent and KSO as an oxidant. This transformation provides a new and...
5.
Zhang Z, Sun H, Zhang M, Song S, Peng M, Dai W, et al.
Org Lett . 2024 May; 26(20):4205-4211. PMID: 38743606
An unprecedented base-controlled selective skeletal rearrangement reaction of hexahydro-4-indol-4-ones has been developed. In this protocol, highly functionalized dihydroxy-4-cyclopenta[]pyridin-4-ones and 8-alkenyl oxepane-2,6-diones were prepared with a broad substrate scope and high...
6.
Chen L, Zhang M, Liu M, Liu Z, Qiu Y, Zhang Z, et al.
Chem Commun (Camb) . 2023 Dec; 60(4):432-435. PMID: 38086626
An efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as a single coupling partner was demonstrated, in which fused benzodiazepine skeletons were obtained in excellent yields. This...
7.
Chen J, Jiang N, Wang T, Xie G, Zhang Z, Li H, et al.
Int J Biol Macromol . 2015 Nov; 82:522-9. PMID: 26526169
Urate oxidase (Uox) is the enzyme involved in purine metabolism. Pseudogenization of Uox gene is the underlying mechanism of hyperuricemia and gout in human. Although Uox from various microorganisms has...