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Fubo Liang

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Articles 15
Citations 523
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Recent Articles
1.
Luo Y, Liang F, Zhang Z
Biochemistry . 2009 Feb; 48(8):1838-46. PMID: 19199380
The PRL (phosphatase of regenerating liver) phosphatases represent a distinct class of protein tyrosine phosphatases, which are implicated in tumorigenesis and metastasis processes. Accumulating evidence indicates that alteration of PRL1...
2.
Liang F, Luo Y, Dong Y, Walls C, Liang J, Jiang H, et al.
J Biol Chem . 2008 Feb; 283(16):10339-46. PMID: 18268019
Phosphatase of regenerating liver 3 (PRL3) is up-regulated in cancer metastases. However, little is known of PRL3-mediated cellular signaling pathways. We previously reported that elevated PRL3 expression increases Src kinase...
3.
Sun J, Luo Y, Yu X, Wang W, Zhou B, Liang F, et al.
J Biol Chem . 2007 Jul; 282(39):29043-29051. PMID: 17656357
The phosphatase of regenerating liver (PRL) phosphatases are implicated in a number of tumorigenesis and metastasis processes. The PRLs are unique among protein-tyrosine phosphatases in that they have extremely low...
4.
Liang F, Kumar S, Zhang Z
Mol Biosyst . 2007 Apr; 3(5):308-16. PMID: 17460790
Protein tyrosine phosphatases (PTPs) constitute a large family of enzymes that play key roles in cell signaling. Deregulation of PTP activity results in aberrant tyrosine phosphorylation, which has been linked...
5.
Liang F, Liang J, Wang W, Sun J, Udho E, Zhang Z
J Biol Chem . 2006 Dec; 282(8):5413-9. PMID: 17192274
Phosphatase of regenerating liver 3 (PRL3) is overexpressed in a variety of tumors, and high levels of PRL3 expression are associated with tumorigenesis and metastasis. Consistent with an oncogenic role...
6.
Kumar S, Zhou B, Liang F, Yang H, Wang W, Zhang Z
J Proteome Res . 2006 Aug; 5(8):1898-905. PMID: 16889411
Protein tyrosine phosphatases (PTPs) consist of a large family of enzymes known to play important roles in controlling virtually all aspects of cellular processes. However, assigning functional significance of PTPs...
7.
Xue C, Liang F, Mahmood R, Vuolo M, Wyckoff J, Qian H, et al.
Cancer Res . 2006 Feb; 66(3):1418-26. PMID: 16452197
A better understanding of how epidermal growth factor receptor family members (ErbBs) contribute to metastasis is important for evaluating ErbB-directed therapies. Activation of ErbB3/ErbB2 heterodimers can affect both proliferation and...
8.
Xue C, Wyckoff J, Liang F, Sidani M, Violini S, Tsai K, et al.
Cancer Res . 2006 Jan; 66(1):192-7. PMID: 16397232
Although overexpression of the epidermal growth factor receptor (EGFR; ErbB1) has been correlated with poor prognosis in breast and other cancers, clinical trials of ErbB1 inhibitors have shown limited efficacy...
9.
Sun J, Wang W, Yang H, Liu S, Liang F, Fedorov A, et al.
Biochemistry . 2005 Sep; 44(36):12009-21. PMID: 16142898
The PRL (phosphatase of regenerating liver) phosphatases constitute a novel class of small, prenylated phosphatases that are implicated in promoting cell growth, differentiation, and tumor invasion, and represent attractive targets...
10.
Lee S, Liang F, Guo X, Xie L, Cahill S, Blumenstein M, et al.
Angew Chem Int Ed Engl . 2005 Jun; 44(27):4242-4. PMID: 15937885
No abstract available.