Frederic Rousseau
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Explore the profile of Frederic Rousseau including associated specialties, affiliations and a list of published articles.
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189
Citations
8989
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Recent Articles
1.
Narykina V, Kleynhans J, Cawthorne C, Schymkowitz J, Rousseau F, Bormans G
EJNMMI Radiopharm Chem
. 2025 Feb;
10(1):10.
PMID: 39982615
Background: The extracellular localisation of the Heat shock protein 90 (Hsp90) is associated with the diseased state and wound healing and presents a promising opportunity for cancer targeting using Positron...
2.
Duran-Romana R, Houben B, Migens P, Zhang Y, Rousseau F, Schymkowitz J
Nat Commun
. 2025 Feb;
16(1):1673.
PMID: 39955309
Because of vectorial protein translation, residues that interact in the native protein structure but are distantly separated in the primary sequence are unavailable simultaneously. Instead, there is a temporal delay...
3.
Khodaparast L, Khodaparast L, Duran-Romana R, Wu G, Houben B, Duverger W, et al.
Nat Commun
. 2025 Feb;
16(1):1561.
PMID: 39939597
Drug-resistant bacteria pose an urgent global health threat, necessitating the development of antibacterial compounds with novel modes of action. Protein biosynthesis accounts for up to half of the energy expenditure...
4.
Delgado J, Reche R, Cianferoni D, Orlando G, van der Kant R, Rousseau F, et al.
Bioinformatics
. 2025 Feb;
41(2).
PMID: 39913370
Motivation: The FoldX force field was originally validated with a database of 1000 mutants at a time when there were few high-resolution structures. Here, we have manually curated a database...
5.
Bollen C, Louwagie S, Deroover F, Duverger W, Khodaparast L, Khodaparast L, et al.
Nat Commun
. 2025 Jan;
16(1):1046.
PMID: 39865082
Recalcitrant bacterial infections can be caused by various types of dormant bacteria, including persisters and viable but nonculturable (VBNC) cells. Despite their clinical importance, we know fairly little about bacterial...
6.
Walkiewicz G, Ronisz A, Ospitalieri S, Tsaka G, Tome S, Vandenberghe R, et al.
Acta Neuropathol Commun
. 2024 Dec;
12(1):194.
PMID: 39707519
The accumulation of abnormal phosphorylated Tau protein (pTau) in neurons of the brain is a pathological hallmark of Alzheimer's disease (AD). PTau pathology also occurs in the retina of AD...
7.
Errico S, Fani G, Ventura S, Schymkowitz J, Rousseau F, Trovato A, et al.
Biochem J
. 2024 Dec;
482(2):87-101.
PMID: 39693572
Advances in solid-state nuclear magnetic resonance (ssNMR) spectroscopy and cryogenic electron microscopy (cryoEM) have revealed the polymorphic nature of the amyloid state of proteins. Given the association of amyloid with...
8.
Holtz A, Van Weyenbergh J, Hong S, Cuypers L, OToole A, Dudas G, et al.
BMC Infect Dis
. 2024 Oct;
24(1):1139.
PMID: 39390446
We investigate the emergence, mutation profile, and dissemination of SARS-CoV-2 lineage B.1.214.2, first identified in Belgium in January 2021. This variant, featuring a 3-amino acid insertion in the spike protein...
9.
Tsaka G, Rousseau F, Schymkowitz J
Cell Rep Med
. 2024 Aug;
5(8):101683.
PMID: 39168096
Levites et al. demonstrate that mouse models of Alzheimer disease (AD), exhibiting amyloid-beta (Αβ) plaque formation, share Αβ responsome proteins with humans. Their work underscores the value of these models...
10.
Duverger W, Tsaka G, Khodaparast L, Khodaparast L, Louros N, Rousseau F, et al.
J Nanobiotechnology
. 2024 Jul;
22(1):406.
PMID: 38987828
Background: Inclusion bodies (IBs) are well-known subcellular structures in bacteria where protein aggregates are collected. Various methods have probed their structure, but single-cell spectroscopy remains challenging. Atomic Force Microscopy-based Infrared...