Frederic Chibon
Overview
Explore the profile of Frederic Chibon including associated specialties, affiliations and a list of published articles.
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Articles
114
Citations
2446
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Recent Articles
1.
Manteaux G, Amsel A, Riquier-Morcant B, Prieto Romero J, Gayte L, Fourneaux B, et al.
Nat Commun
. 2024 Sep;
15(1):7940.
PMID: 39266552
Dedifferentiated and Well-differentiated liposarcoma are characterized by a systematic amplification of the Murine Double Minute 2 (MDM2) oncogene. We demonstrate that p53-independent metabolic functions of chromatin-bound MDM2 are exacerbated in...
2.
Fontanges Q, Dubos P, Lesluyes T, Laizet Y, Velasco V, Melendez B, et al.
Genes Chromosomes Cancer
. 2024 Mar;
63(3):e23229.
PMID: 38481055
A close relationship has been demonstrated between genomic complexity and clinical outcome in uterine smooth muscle tumors. We studied the genomic profiles by array-CGH of 28 fumarate hydratase deficient leiomyomas...
3.
Ferron G, Bataillon G, Martinez A, Chibon F, Valentin T
Int J Gynecol Cancer
. 2024 Mar;
34(3):393-402.
PMID: 38438176
Adult-type gynecological soft tissue and visceral sarcomas are rare tumors, with an estimated incidence of 13% of all sarcomas and 4% of all gynecological malignancies. They most often develop in...
4.
Feng X, Tonon L, Li H, Darbo E, Pleasance E, Macagno N, et al.
Cancers (Basel)
. 2023 Jul;
15(14).
PMID: 37509366
To investigate the immune biomarker in Leiomyosarcoma (LMS), which is rare and recognized as an immune cold cancer showing a poor response rate (<10%) to immune checkpoint inhibitors (ICIs). However,...
5.
Michot A, Lagarde P, Lesluyes T, Darbo E, Neuville A, Baud J, et al.
Cancers (Basel)
. 2023 Jul;
15(13).
PMID: 37444560
Background: The management of soft-tissue sarcoma (STS) relies on a multidisciplinary approach involving specialized oncological surgery combined with other adjuvant therapies to achieve optimal local disease control. Purpose and Results:...
6.
Poumeaud F, Valentin T, Vande Perre P, Jaffrelot M, Bonnet D, Chibon F, et al.
Crit Rev Oncol Hematol
. 2023 Jun;
188:104055.
PMID: 37301271
Lynch syndrome (LS) is a genetic predisposition leading to colorectal and non-colorectal tumors such as endometrial, upper urinary tract, small intestine, ovarian, gastric, biliary duct cancers and glioblastoma. Though not...
7.
Labrousse G, Vande Perre P, Parra G, Jaffrelot M, Leroy L, Chibon F, et al.
NAR Cancer
. 2023 Mar;
5(2):zcad011.
PMID: 36915289
The exonuclease domain of DNA polymerases epsilon's catalytic subunit (POLE) removes misincorporated nucleotides, called proofreading. POLE-exonuclease mutations cause colorectal- and endometrial cancers with an extreme burden of single nucleotide substitutions....
8.
Darbo E, Perot G, Darmusey L, Le Guellec S, Leroy L, Gaston L, et al.
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672483
In leiomyosarcoma (LMS), a very aggressive disease, a relatively transcriptionally uniform subgroup of well-differentiated tumors has been described and is associated with poor survival. The question raised how differentiation and...
9.
Brunac A, Fourquet J, Perot G, Jaffrelot M, Meilleroux J, Danjoux M, et al.
Mod Pathol
. 2022 Oct;
35(12):2002-2010.
PMID: 36202996
The outcome of stage II-III colorectal cancer (CRC) is highly variable and therapeutic choice is currently based on TNM staging with a few additional biomarkers. However, studies show that some...
10.
Feng X, Li H, Fourquet J, Brahmi M, Dufresne A, Meurgey A, et al.
JCO Precis Oncol
. 2022 Aug;
6:e2200129.
PMID: 36001861
Purpose: To investigate the use of PTEN biomarker to improve prognostic stratification in patients with localized gastrointestinal stromal tumor (GIST). Methods: PTEN expression and genomic analysis were performed on two...