Franka Voigt
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Explore the profile of Franka Voigt including associated specialties, affiliations and a list of published articles.
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13
Citations
469
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Recent Articles
1.
Gomez-Puerta S, Ferrero R, Hochstoeger T, Zubiri I, Chao J, Aragon T, et al.
Elife
. 2022 Jun;
11.
PMID: 35730412
Endoplasmic reticulum (ER) to nucleus homeostatic signaling, known as the unfolded protein response (UPR), relies on the non-canonical splicing of XBP1 mRNA. The molecular switch that initiates splicing is the...
2.
Zinnall U, Milek M, Minia I, Vieira-Vieira C, Muller S, Mastrobuoni G, et al.
Nat Commun
. 2022 May;
13(1):2727.
PMID: 35585045
The biological role of RNA-binding proteins in the secretory pathway is not well established. Here, we describe that human HDLBP/Vigilin directly interacts with more than 80% of ER-localized mRNAs. PAR-CLIP...
3.
Mateju D, Eichenberger B, Voigt F, Eglinger J, Roth G, Chao J
Cell
. 2020 Dec;
183(7):1801-1812.e13.
PMID: 33308477
Cellular stress leads to reprogramming of mRNA translation and formation of stress granules (SGs), membraneless organelles consisting of mRNA and RNA-binding proteins. Although the function of SGs remains largely unknown,...
4.
Voigt F, Eglinger J, Chao J
Methods Mol Biol
. 2019 Aug;
2038:75-88.
PMID: 31407279
mRNA turnover plays an important role in the regulation of post-transcriptional gene expression. While many protein factors involved in mRNA degradation have been identified, we still lack a basic understanding...
5.
Voigt F, Gerbracht J, Boehm V, Horvathova I, Eglinger J, Chao J, et al.
Nat Protoc
. 2019 Apr;
14(5):1603-1633.
PMID: 31019309
RNA degradation ensures appropriate levels of mRNA transcripts within cells and eliminates aberrant RNAs. Detailed studies of RNA degradation dynamics have been heretofore infeasible because of the inherent instability of...
6.
Wilbertz J, Voigt F, Horvathova I, Roth G, Zhan Y, Chao J
Mol Cell
. 2019 Jan;
73(5):946-958.e7.
PMID: 30661979
Biological phase transitions form membrane-less organelles that generate distinct cellular environments. How molecules are partitioned between these compartments and the surrounding cellular space and the functional consequence of this localization...
7.
Voigt F, Zhang H, Cui X, Triebold D, Liu A, Eglinger J, et al.
Cell Rep
. 2017 Dec;
21(13):3740-3753.
PMID: 29281824
It is well established that mRNAs encoding secretory or membrane-bound proteins are translated on the surface of the endoplasmic reticulum (ER). The extent to which mRNAs that encode cytosolic proteins...
8.
Voigt F, Eglinger J, Chao J
Methods Mol Biol
. 2017 Nov;
1649:373-384.
PMID: 29130211
Quantitative fluorescence microscopy techniques are frequently applied to answer fundamental biological questions. Single-molecule RNA imaging methods have enabled the direct observation of the initial steps of the mRNA life cycle...
9.
Horvathova I, Voigt F, Kotrys A, Zhan Y, Artus-Revel C, Eglinger J, et al.
Mol Cell
. 2017 Oct;
68(3):615-625.e9.
PMID: 29056324
RNA degradation plays a fundamental role in regulating gene expression. In order to characterize the spatiotemporal dynamics of RNA turnover in single cells, we developed a fluorescent biosensor based on...
10.
Schulz E, Seiler M, Zuliani C, Voigt F, Rybin V, Pogenberg V, et al.
Sci Rep
. 2017 Aug;
7(1):9903.
PMID: 28852099
The RNA-chaperone Hfq catalyses the annealing of bacterial small RNAs (sRNAs) with target mRNAs to regulate gene expression in response to environmental stimuli. Hfq acts on a diverse set of...