Francois Kroll
Overview
Explore the profile of Francois Kroll including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
116
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Recent Articles
1.
Kroll F, Donnelly J, Ozcan G, Mackay E, Rihel J
Elife
. 2025 Feb;
13.
PMID: 39960847
By exposing genes associated with disease, genomic studies provide hundreds of starting points that should lead to druggable processes. However, our ability to systematically translate these genomic findings into biological...
2.
Kempthorne L, Vaizoglu D, Cammack A, Carcole M, Roberts M, Mikheenko A, et al.
Nat Commun
. 2025 Jan;
16(1):459.
PMID: 39779704
The most common genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) is an intronic GC repeat expansion in C9orf72. The repeats undergo bidirectional transcription to produce sense...
3.
Tornini V, Miao L, Lee H, Gerson T, Dube S, Schmidt V, et al.
Elife
. 2023 May;
12.
PMID: 37191016
Thousands of long intergenic non-coding RNAs (lincRNAs) are transcribed throughout the vertebrate genome. A subset of lincRNAs enriched in developing brains have recently been found to contain cryptic open-reading frames...
4.
Kroll F, Dimitriadis A, Campbell T, Darwent L, Collinge J, Mead S, et al.
Sci Rep
. 2022 May;
12(1):8284.
PMID: 35585119
Prion diseases are fatal neurodegenerative conditions that affect humans and animals. Rapid and accurate sequencing of the prion gene PRNP is paramount to human prion disease diagnosis and for animal...
5.
Kroll F, Powell G, Ghosh M, Gestri G, Antinucci P, Hearn T, et al.
Elife
. 2021 Jan;
10.
PMID: 33416493
Hundreds of human genes are associated with neurological diseases, but translation into tractable biological mechanisms is lagging. Larval zebrafish are an attractive model to investigate genetic contributions to neurological diseases....