Charles E Vejnar
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Explore the profile of Charles E Vejnar including associated specialties, affiliations and a list of published articles.
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30
Citations
2553
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Recent Articles
1.
Boraas L, Hu M, Martino P, Thornton L, Vejnar C, Zhen G, et al.
Cell Rep
. 2025 Jan;
44(2):115237.
PMID: 39883578
The subcellular localization of mRNAs plays a pivotal role in biological processes, including cell migration. For instance, β-actin mRNA and its associated RNA-binding protein (RBP), ZBP1/IGF2BP1, are recruited to focal...
2.
Fuentes R, Marlow F, Abrams E, Zhang H, Kobayashi M, Gupta T, et al.
PLoS Genet
. 2024 Jul;
20(7):e1011343.
PMID: 39052672
Maternally-loaded factors in the egg accumulate during oogenesis and are essential for the acquisition of oocyte and egg developmental competence to ensure the production of viable embryos. However, their molecular...
3.
Musaev D, Abdelmessih M, Vejnar C, Yartseva V, Weiss L, Strayer E, et al.
Cell Rep
. 2024 Apr;
43(4):114074.
PMID: 38625794
Post-transcriptional mRNA regulation shapes gene expression, yet how cis-elements and mRNA translation interface to regulate mRNA stability is poorly understood. We find that the strength of translation initiation, upstream open...
4.
Pownall M, Miao L, Vejnar C, MSaad O, Sherrard A, Frederick M, et al.
Science
. 2023 Jul;
381(6653):92-100.
PMID: 37410825
Nanoscale chromatin organization regulates gene expression. Although chromatin is notably reprogrammed during zygotic genome activation (ZGA), the organization of chromatin regulatory factors during this universal process remains unclear. In this...
5.
Tornini V, Miao L, Lee H, Gerson T, Dube S, Schmidt V, et al.
Elife
. 2023 May;
12.
PMID: 37191016
Thousands of long intergenic non-coding RNAs (lincRNAs) are transcribed throughout the vertebrate genome. A subset of lincRNAs enriched in developing brains have recently been found to contain cryptic open-reading frames...
6.
Bogoch Y, Jamieson-Lucy A, Vejnar C, Levy K, Giraldez A, Mullins M, et al.
Front Cell Dev Biol
. 2022 Jun;
10:826892.
PMID: 35733854
Oogenesis produces functional eggs and is essential for fertility, embryonic development, and reproduction. The zebrafish ovary is an excellent model to study oogenesis in vertebrates, and recent studies have identified...
7.
Vicencio J, Sanchez-Bolanos C, Moreno-Sanchez I, Brena D, Vejnar C, Kukhtar D, et al.
Nat Commun
. 2022 May;
13(1):2601.
PMID: 35552388
The requirement for Cas nucleases to recognize a specific PAM is a major restriction for genome editing. SpCas9 variants SpG and SpRY, recognizing NGN and NRN PAMs, respectively, have contributed...
8.
Miao L, Tang Y, Bonneau A, Chan S, Kojima M, Pownall M, et al.
Mol Cell
. 2022 Feb;
82(5):986-1002.e9.
PMID: 35182480
Upon fertilization, embryos undergo chromatin reprogramming and genome activation; however, the mechanisms that regulate these processes are poorly understood. Here, we generated a triple mutant for Nanog, Pou5f3, and Sox19b...
9.
Jamieson-Lucy A, Kobayashi M, Aykit Y, Elkouby Y, Escobar-Aguirre M, Vejnar C, et al.
Dev Biol
. 2022 Jan;
484:1-11.
PMID: 35065906
The Balbiani body (Bb) is the first marker of polarity in vertebrate oocytes. The Bb is a conserved structure found in diverse animals including insects, fish, amphibians, and mammals. During...
10.
Vejnar C, Giraldez A
Bioinformatics
. 2020 Jun;
36(16):4530-4531.
PMID: 32502232
Summary: Experimental laboratory management and data-driven science require centralized software for sharing information, such as lab collections or genomic sequencing datasets. Although database servers such as PostgreSQL can store such...