Francisco J Planes
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Explore the profile of Francisco J Planes including associated specialties, affiliations and a list of published articles.
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50
Citations
1037
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Recent Articles
1.
Valcarcel L, Jose-Eneriz E, Ordonez R, Apaolaza I, Olaverri-Mendizabal D, Barrena N, et al.
Nat Commun
. 2024 Oct;
15(1):8685.
PMID: 39394196
The development of computational tools for the systematic prediction of metabolic vulnerabilities of cancer cells constitutes a central question in systems biology. Here, we present gmctool, a freely accessible online...
2.
Martinez-Gonzalez M, Planes F, Ruiz-Canela M, Toledo E, Estruch R, Salas-Salvado J, et al.
Rev Esp Cardiol (Engl Ed)
. 2024 Oct;
78(3):263-271.
PMID: 39357800
A growing body of research on nutrition omics has led to recent advances in cardiovascular disease epidemiology and prevention. Within the PREDIMED trial, significant associations between diet-related metabolites and cardiovascular...
3.
Gomez-Echarte N, Jose-Eneriz E, Carrasco-Leon A, Barrena N, Miranda E, Garate L, et al.
Haematologica
. 2024 Sep;
110(2):514-519.
PMID: 39323408
No abstract available.
4.
Balzerani F, Blasco T, Perez-Burillo S, Francino M, Rufian-Henares J, Valcarcel L, et al.
Bioinformatics
. 2024 Jul;
40(11).
PMID: 39018187
Motivation: 16S rRNA gene sequencing is the most frequent approach for the characterization of the human gut microbiota. Despite different efforts in the literature, the inference of functional and metabolic...
5.
Extending PROXIMAL to predict degradation pathways of phenolic compounds in the human gut microbiota
Balzerani F, Blasco T, Perez-Burillo S, Valcarcel L, Hassoun S, Planes F
NPJ Syst Biol Appl
. 2024 May;
10(1):56.
PMID: 38802371
Despite significant advances in reconstructing genome-scale metabolic networks, the understanding of cellular metabolism remains incomplete for many organisms. A promising approach for elucidating cellular metabolism is analysing the full scope...
6.
Rodriguez-Flores C, Barrena N, Olaverri-Mendizabal D, Ochoa I, Valcarcel L, Planes F
Bioinformatics
. 2024 May;
40(6).
PMID: 38748994
Motivation: The identification of minimal genetic interventions that modulate metabolic processes constitutes one of the most relevant applications of genome-scale metabolic models (GEMs). The concept of Minimal Cut Sets (MCSs)...
7.
Blasco T, Balzerani F, Valcarcel L, Larranaga P, Bielza C, Francino M, et al.
Bioinformatics
. 2024 Apr;
40(5).
PMID: 38688585
Motivation: Simulating gut microbial dynamics is extremely challenging. Several computational tools, notably the widely used BacArena, enable modeling of dynamic changes in the microbial environment. These methods, however, do not...
8.
Olaverri-Mendizabal D, Valcarcel L, Barrena N, Rodriguez C, Planes F
Brief Bioinform
. 2024 Mar;
25(3).
PMID: 38546323
Cancer metabolism is a marvellously complex topic, in part, due to the reprogramming of its pathways to self-sustain the malignant phenotype in the disease, to the detriment of its healthy...
9.
Synthetic lethality in large-scale integrated metabolic and regulatory network models of human cells
Barrena N, Valcarcel L, Olaverri-Mendizabal D, Apaolaza I, Planes F
NPJ Syst Biol Appl
. 2023 Jul;
9(1):32.
PMID: 37454223
Synthetic lethality (SL) is a promising concept in cancer research. A wide array of computational tools has been developed to predict and exploit synthetic lethality for the identification of tumour-specific...
10.
San Juan I, Pereira-Ortuzar T, Cendoya X, Lain A, To-Figueras J, Mateos B, et al.
Biochemistry
. 2022 Oct;
61(21):2409-2416.
PMID: 36241173
Patients with major forms of acute hepatic porphyria present acute neurological attacks with overproduction of porphobilinogen (PBG) and δ-aminolevulinic acid (ALA). Even if ALA is considered the most likely agent...