Francesca Sanvito
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Explore the profile of Francesca Sanvito including associated specialties, affiliations and a list of published articles.
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93
Citations
3698
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Recent Articles
11.
Tupini C, Chilin A, Rossi A, De Fino I, Bragonzi A, DAversa E, et al.
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430961
A series of new-generation TMA (4,6,4'-trimethyl angelicin) analogues was projected and synthetized in order to ameliorate anti-inflammatory activity, with reduced or absent toxicity. Since the NF-κB transcription factor (TF) plays...
12.
Trudu M, Oliva L, Orfanelli U, Romano A, Di Raimondo F, Sanvito F, et al.
Front Oncol
. 2022 Sep;
12:968208.
PMID: 36172163
Multiple myeloma grows by establishing multiple interactions with bone marrow cells. These include expansion of myeloid-derived suppressor cells, which drive immunoevasion mechanisms that include arginase-1-driven depletion of L-arginine, thus indirectly...
13.
Fragasso G, Sanvito F, Monaca G, Ardizzone V, De Bonis M, Pappalardo F, et al.
J Cardiovasc Med (Hagerstown)
. 2022 Jul;
23(8):505-512.
PMID: 35904996
Background: Chronic heart valve regurgitation induces left ventricular (LV) volume overload, leading to the development of hypertrophy and progressive dilatation of the ventricle to maintain physiological cardiac output. In order...
14.
Birocchi F, Cusimano M, Rossari F, Beretta S, Rancoita P, Ranghetti A, et al.
Sci Transl Med
. 2022 Jul;
14(653):eabl4106.
PMID: 35857642
Glioblastoma multiforme (GBM) is the most common and lethal brain tumor characterized by a strongly immunosuppressive tumor microenvironment (TME) that represents a barrier also for the development of effective immunotherapies....
15.
Russo F, Ruggiero E, Curto R, Passeri L, Sanvito F, Bortolomai I, et al.
Mol Ther Methods Clin Dev
. 2022 May;
25:508-519.
PMID: 35615710
Insulin is the primary autoantigen (Ag) targeted by T cells in type 1 diabetes (T1D). Although biomarkers precisely identifying subjects at high risk of T1D are available, successful prophylaxis is...
16.
Arcangeli S, Bove C, Mezzanotte C, Camisa B, Falcone L, Manfredi F, et al.
J Clin Invest
. 2022 May;
132(12).
PMID: 35503659
Chimeric antigen receptor (CAR) T cell expansion and persistence represent key factors to achieve complete responses and prevent relapses. These features are typical of early memory T cells, which can...
17.
Ruggiero E, Carnevale E, Prodeus A, Magnani Z, Camisa B, Merelli I, et al.
Sci Transl Med
. 2022 Feb;
14(631):eabg8027.
PMID: 35138911
T cell receptor (TCR)-based therapy has the potential to induce durable clinical responses in patients with cancer by targeting intracellular tumor antigens with high sensitivity and by promoting T cell...
18.
Genchi A, Semerano A, Schwarz G, DellAcqua B, Gullotta G, Sampaolo M, et al.
Acta Neuropathol Commun
. 2022 Feb;
10(1):14.
PMID: 35105380
Coronavirus disease 2019 (COVID-19) is associated with an increased risk of thrombotic events. Ischemic stroke in COVID-19 patients entails high severity and mortality rates. Here we aimed to analyze cerebral...
19.
Greco B, Malacarne V, De Girardi F, Scotti G, Manfredi F, Angelino E, et al.
Sci Transl Med
. 2022 Jan;
14(628):eabg3072.
PMID: 35044789
Immunotherapy with chimeric antigen receptor (CAR)–engineered T cells showed exceptional successes in patients with refractory B cell malignancies. However, first-in-human studies in solid tumors revealed unique hurdles contributing to poor...
20.
Mariotton J, Sams A, Cohen E, Sennepin A, Siracusano G, Sanvito F, et al.
Front Immunol
. 2021 Dec;
12:785072.
PMID: 34956215
Background: The vasodilator neuropeptide calcitonin gene-related peptide (CGRP) plays both detrimental and protective roles in different pathologies. CGRP is also an essential component of the neuro-immune dialogue between nociceptors and...