Fotini Gounari
Overview
Explore the profile of Fotini Gounari including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
60
Citations
2798
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tousinas G, Olumide Emmanuel A, Tracy M, Arnovitz S, Friedman D, Papamarcaki T, et al.
J Immunol
. 2024 Jul;
213(5):641-650.
PMID: 38958395
Activation of β-catenin in CD4+CD8+ double-positive (DP) thymocytes halts development before the thymic selection stage and predisposes to transformation. Leukemogenesis, but not the developmental block, depends on TCF-1, β-catenin's DNA-binding...
2.
Pollard J, Hynes G, Yin D, Mandal M, Gounari F, Alegre M, et al.
JCI Insight
. 2024 May;
9(13).
PMID: 38771643
Alloreactive memory, unlike naive, CD8+ T cells resist transplantation tolerance protocols and are a critical barrier to long-term graft acceptance in the clinic. We here show that semiallogeneic pregnancy successfully...
3.
Pollard J, Hynes G, Yin D, Mandal M, Gounari F, Alegre M, et al.
Res Sq
. 2023 Apr;
PMID: 37066154
Alloreactive memory T cells, unlike naive T cells, fail to be restrained by transplantation tolerance protocols or regulatory T cells, and therefore represent a critical barrier to long-term graft acceptance....
4.
Arnovitz S, Mathur P, Tracy M, Mohsin A, Mondal S, Quandt J, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(32):e2201493119.
PMID: 35921443
Understanding the mechanisms promoting chromosomal translocations of the rearranging receptor loci in leukemia and lymphoma remains incomplete. Here we show that leukemias induced by aberrant activation of β-catenin in thymocytes,...
5.
Gounari F, Khazaie K
Nat Immunol
. 2022 Apr;
23(5):671-678.
PMID: 35487986
The T cell-specific DNA-binding protein TCF-1 is a central regulator of T cell development and function along multiple stages and lineages. Because it interacts with β-catenin, TCF-1 has been classically...
6.
Osman A, Yan B, Li Y, Pavelko K, Quandt J, Saadalla A, et al.
Nat Immunol
. 2021 Aug;
22(9):1152-1162.
PMID: 34385712
The transcription factor TCF-1 is essential for the development and function of regulatory T (T) cells; however, its function is poorly understood. Here, we show that TCF-1 primarily suppresses transcription...
7.
Quandt J, Arnovitz S, Haghi L, Woehlk J, Mohsin A, Okoreeh M, et al.
Nat Immunol
. 2021 Mar;
22(4):471-484.
PMID: 33664518
The diversity of regulatory T (T) cells in health and in disease remains unclear. Individuals with colorectal cancer harbor a subpopulation of RORγt T cells with elevated expression of β-catenin...
8.
9.
Kong D, Wan Q, Li J, Zuo S, Liu G, Liu Q, et al.
Circulation
. 2020 Jan;
141(8):655-666.
PMID: 31893939
Background: Blood pressure often rises with aging, but exact mechanisms are still not completely understood. With aging, the level of proinflammatory cytokines increases in T lymphocytes. Prostaglandin D, a proresolution...
10.
Saadalla A, Lima M, Tsai F, Osman A, Singh M, Linden D, et al.
Front Immunol
. 2019 Dec;
10:2777.
PMID: 31849960
Mast cells constitutively express ß-catenin and expand in solid tumors such as colon and skin cancer. However, the role of ß-catenin signaling in mast cells and the cause or effect...