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Florian H Leinberger

Explore the profile of Florian H Leinberger including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 31
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Recent Articles
1.
Leinberger F, Cassidy L, Edelmann D, Schmid N, Oberpaul M, Blumenkamp P, et al.
mSystems . 2024 Oct; 9(11):e0106024. PMID: 39377584
Importance: Protein aggregates occur in all living cells due to misfolding of proteins. In bacteria, protein aggregation is associated with cellular inactivity, which is related to dormancy and tolerance to...
2.
Leinberger F, Berghoff B
Sci Rep . 2024 Oct; 14(1):22998. PMID: 39362964
Bacterial dormancy is marked by reduced cellular activity and the suspension of growth. It represents a valuable strategy to survive stressful conditions, as exemplified by the long-term tolerance towards antibiotics...
3.
Shore S, Leinberger F, Fozo E, Berghoff B
EcoSal Plus . 2024 May; 12(1):eesp00252022. PMID: 38767346
Toxin-antitoxin systems are ubiquitous in the prokaryotic world and widely distributed among chromosomes and mobile genetic elements. Several different toxin-antitoxin system types exist, but what they all have in common...
4.
Windfelder A, Muller F, Larney B, Hentschel M, Bohringer A, von Bredow C, et al.
Nat Commun . 2022 Nov; 13(1):7216. PMID: 36433960
Mammalian models of human disease are expensive and subject to ethical restrictions. Here, we present an independent platform for high-throughput screening, using larvae of the tobacco hornworm Manduca sexta, combining...
5.
Edelmann D, Leinberger F, Schmid N, Oberpaul M, Schaberle T, Berghoff B
Microorganisms . 2021 Apr; 9(5). PMID: 33925723
Bacterial chromosomes harbor toxin-antitoxin (TA) systems, some of which are implicated in the formation of multidrug-tolerant persister cells. In , toxin TisB from the / TA system depolarizes the inner...
6.
Gokyildirim M, Grandel U, Hattar K, Dahlem G, Schuetz E, Leinberger F, et al.
Oncotarget . 2018 Jul; 9(48):28976-28988. PMID: 29989005
Non-small cell lung cancer (NSCLC) has a very poor prognosis even when treated with the best therapies available today often including radiation. NSCLC is frequently complicated by pulmonary infections which...
7.
Eberle F, Leinberger F, Saulich M, Seeger W, Engenhart-Cabillic R, Hanze J, et al.
Clin Transl Radiat Oncol . 2018 Apr; 2:69-75. PMID: 29658004
Background And Purpose: The SCF/c-Kit pathway is often overexpressed in human tumors leading to an enhanced tumorigenesis, proliferation and migration. It was now tested for NSCLC and prostate cancer cells...
8.
Eberle F, Saulich M, Leinberger F, Seeger W, Engenhart-Cabillic R, Dikomey E, et al.
Radiother Oncol . 2016 May; 119(3):537-43. PMID: 27178146
Background And Purpose: Success of radiotherapy is often limited by therapy resistance and metastasis resulting from cancer cell motility. It was tested in vitro whether this cancer cell motility is...