Daniel Edelmann
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Explore the profile of Daniel Edelmann including associated specialties, affiliations and a list of published articles.
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8
Citations
75
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Recent Articles
1.
Leinberger F, Cassidy L, Edelmann D, Schmid N, Oberpaul M, Blumenkamp P, et al.
mSystems
. 2024 Oct;
9(11):e0106024.
PMID: 39377584
Importance: Protein aggregates occur in all living cells due to misfolding of proteins. In bacteria, protein aggregation is associated with cellular inactivity, which is related to dormancy and tolerance to...
2.
Edelmann D, Berghoff B
Front Microbiol
. 2022 Apr;
13:871699.
PMID: 35369430
Bacterial persistence is a phenomenon that is founded by the existence of a subpopulation of multidrug-tolerant cells. These so-called persister cells endure otherwise lethal stress situations and enable restoration of...
3.
Edelmann D, Leinberger F, Schmid N, Oberpaul M, Schaberle T, Berghoff B
Microorganisms
. 2021 Apr;
9(5).
PMID: 33925723
Bacterial chromosomes harbor toxin-antitoxin (TA) systems, some of which are implicated in the formation of multidrug-tolerant persister cells. In , toxin TisB from the / TA system depolarizes the inner...
4.
Edelmann D, Oberpaul M, Schaberle T, Berghoff B
Environ Microbiol Rep
. 2020 Dec;
13(2):159-168.
PMID: 33350069
Bacterial dormancy is a valuable strategy to endure unfavourable conditions. The term 'persister' has been coined for cells that tolerate antibiotic treatments due to reduced cellular activity. The type I...
5.
Li S, Edelmann D, Berghoff B, Georg J, Evguenieva-Hackenberg E
RNA Biol
. 2020 Nov;
18(9):1324-1338.
PMID: 33164661
DnaA is the initiator protein of chromosome replication, but the regulation of its homoeostasis in enterobacteria is not well understood. The DnaA level remains stable at different growth rates, suggesting...
6.
Type I toxin-dependent generation of superoxide affects the persister life cycle of Escherichia coli
Edelmann D, Berghoff B
Sci Rep
. 2019 Oct;
9(1):14256.
PMID: 31582786
Induction of growth stasis by bacterial toxins from chromosomal toxin-antitoxin systems is suspected to favor formation of multidrug-tolerant cells, named persisters. Recurrent infections are often attributed to resuscitation and regrowth...
7.
Spanka D, Konzer A, Edelmann D, Berghoff B
Front Microbiol
. 2019 Mar;
10:378.
PMID: 30894840
Bacterial populations produce phenotypic variants called persisters to survive harmful conditions. Persisters are highly tolerant to antibiotics and repopulate environments after the stress has vanished. In order to resume growth,...
8.
Schuebel F, Rocker A, Edelmann D, Schessner J, Brieke C, Meinhart A
J Biol Chem
. 2016 Sep;
291(44):22868-22880.
PMID: 27621317
An arsenal of effector proteins is injected by bacterial pathogens into the host cell or its vicinity to increase virulence. The commonly used top-down approaches inferring the toxic mechanism of...