Florentine S B Subtil
Overview
Explore the profile of Florentine S B Subtil including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
197
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0
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Recent Articles
1.
Kohl S, Subtil F, Climenti V, Anees H, Parplys A, Engenhart-Cabillic R, et al.
Transl Oncol
. 2025 Mar;
55:102359.
PMID: 40088750
Objectives: Human papilloma virus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) cells are highly radiosensitive resulting from an elevated number of DNA double-strand breaks (DSB) remaining after irradiation. Partially...
2.
Hanze J, Mengen L, Mernberger M, Tiwari D, Plagge T, Nist A, et al.
Radiat Oncol
. 2024 Jul;
19(1):85.
PMID: 38956684
Background: Radiotherapy is essential in the treatment of prostate cancer. An alternative to conventional photon radiotherapy is the application of carbon ions, which provide a superior intratumoral dose distribution and...
3.
Subtil F, Grobner C, Recknagel N, Parplys A, Kohl S, Arenz A, et al.
Cancers (Basel)
. 2022 Jul;
14(13).
PMID: 35804930
The standard of care for advanced head and neck cancers (HNSCCs) is radiochemotherapy, including cisplatin. This treatment results in a cure rate of approximately 85% for oropharyngeal HPV-positive HNSCCs, in...
4.
Tiwari D, Hannen R, Unger K, Kohl S, Hess J, Lauber K, et al.
Front Oncol
. 2022 May;
12:878675.
PMID: 35530351
Background: Treatment of locally advanced HPV-negative head and neck squamous cell carcinoma (HNSCC) with photon radiation is the standard of care but shows only moderate success. Alterations in response toward...
5.
Eberle F, Engenhart-Cabillic R, Schymalla M, Dumke C, Schotz U, Subtil F, et al.
Front Oncol
. 2022 Mar;
12:814082.
PMID: 35242709
Background: Surgery and radiotherapy are current therapeutic options for malignant tumors involving the nasal vestibule. Depending on the location, organ-preserving resection is not always possible, even for small tumors. Definitive...
6.
Lerch S, Berthold S, Ziemann F, Dreffke K, Subtil F, Senger Y, et al.
Radiother Oncol
. 2020 Jul;
151:134-140.
PMID: 32717362
Background And Purpose: HPV positive (pos.) HNSCC cells are significantly more radiosensitive to photon irradiation as compared to HPV negative (neg.) cells. Functionally, this is considered to result from a...
7.
Schotz U, Balzer V, Brandt F, Ziemann F, Subtil F, Rieckmann T, et al.
Cancers (Basel)
. 2020 Feb;
12(2).
PMID: 32085396
The PI3K/Akt/mTOR pathway is frequently altered in human papillomavirus (HPV)-positive and negative squamous cell carcinoma of the head and neck (HNSCC) and overstimulation is associated with poor prognosis. PI3K drives...
8.
Gokyildirim M, Grandel U, Hattar K, Dahlem G, Schuetz E, Leinberger F, et al.
Oncotarget
. 2018 Jul;
9(48):28976-28988.
PMID: 29989005
Non-small cell lung cancer (NSCLC) has a very poor prognosis even when treated with the best therapies available today often including radiation. NSCLC is frequently complicated by pulmonary infections which...
9.
Eberle F, Leinberger F, Saulich M, Seeger W, Engenhart-Cabillic R, Hanze J, et al.
Clin Transl Radiat Oncol
. 2018 Apr;
2:69-75.
PMID: 29658004
Background And Purpose: The SCF/c-Kit pathway is often overexpressed in human tumors leading to an enhanced tumorigenesis, proliferation and migration. It was now tested for NSCLC and prostate cancer cells...
10.
Ziemann F, Seltzsam S, Dreffke K, Preising S, Arenz A, Subtil F, et al.
Oncotarget
. 2017 Dec;
8(62):105170-105183.
PMID: 29285242
At present, advanced stage human Papillomavirus (HPV) negative and positive head and neck squamous cell carcinoma (HNSCC) are treated by intense multimodal therapy that includes radiochemotherapy, which are associated with...