Florian D Schubot
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Explore the profile of Florian D Schubot including associated specialties, affiliations and a list of published articles.
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26
Citations
374
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Recent Articles
1.
Salar S, Ball N, Baaziz H, Nix J, Sobe R, Compton K, et al.
Proteins
. 2023 May;
91(10):1394-1406.
PMID: 37213073
Chemotaxis is a fundamental process whereby bacteria seek out nutrient sources and avoid harmful chemicals. For the symbiotic soil bacterium Sinorhizobium meliloti, the chemotaxis system also plays an essential role...
2.
Salar S, Schubot F
Methods Enzymol
. 2023 Jan;
679:1-32.
PMID: 36682859
Bacterial pathogens such as Pseudomonas aeruginosa use complex regulatory networks to tailor gene expression patterns to meet complex environmental challenges. P. aeruginosa is capable of causing both acute and chronic...
3.
Ryan Kaler K, Nix J, Schubot F
J Biol Chem
. 2021 Sep;
297(4):101193.
PMID: 34529974
Bacterial signaling histidine kinases (HKs) have long been postulated to function exclusively through linear signal transduction chains. However, several HKs have recently been shown to form complex multikinase networks (MKNs)....
4.
Shrestha M, Bernhards R, Fu Y, Ryan K, Schubot F
Sci Rep
. 2020 Jun;
10(1):9881.
PMID: 32555263
The type III secretion system (T3SS) is a pivotal virulence mechanism of many Gram-negative bacteria. During infection, the syringe-like T3SS injects cytotoxic proteins directly into the eukaryotic host cell cytoplasm....
5.
Mancl J, Ray W, Helm R, Schubot F
Structure
. 2019 Mar;
27(5):785-793.e5.
PMID: 30879888
Recent paradigm shifting discoveries have demonstrated that bacterial signaling kinases engage in unexpected regulatory crosstalk, yet the underlying molecular mechanisms remain largely uncharacterized. The Pseudomonas aeruginosa RetS/GacS system constitutes an...
6.
Shrestha M, Compton K, Mancl J, Webb B, Brown A, Scharf B, et al.
Biochem J
. 2018 Nov;
475(24):3949-3962.
PMID: 30442721
The α-proteobacterium can live freely in the soil or engage in a symbiosis with its legume host. facilitates nitrogen fixation in root nodules, thus providing pivotal, utilizable nitrogen to the...
7.
Black W, Wang L, Jing X, Saldana R, Li F, Scharf B, et al.
Sci Rep
. 2017 Aug;
7(1):7263.
PMID: 28779124
Myxococcus xanthus possesses a form of surface motility powered by the retraction of the type IV pilus (T4P). Additionally, exopolysaccharide (EPS), the major constituent of bacterial biofilms, is required for...
8.
Stevens A, Smith A, Marbach-Ad G, Balcom S, Buchner J, Daniel S, et al.
J Microbiol Biol Educ
. 2017 May;
18(1).
PMID: 28512513
Misconceptions, also known as alternate conceptions, about key concepts often hinder the ability of students to learn new knowledge. Concept inventories (CIs) are designed to assess students' understanding of key...
9.
Mancl J, Black W, Robinson H, Yang Z, Schubot F
Structure
. 2016 Sep;
24(11):1886-1897.
PMID: 27667690
Type IV pili (T4P) mediate bacterial motility and virulence. The PilB/GspE family ATPases power the assembly of T4P and type 2 secretion systems. We determined the structure of the ATPase...
10.
Shrestha M, Xiao Y, Robinson H, Schubot F
PLoS One
. 2015 Aug;
10(8):e0136533.
PMID: 26317977
Pseudomonas aeruginosa employs a type three secretion system to facilitate infections in mammalian hosts. The operons encoding genes of structural components of the secretion machinery and associated virulence factors are...