Flore Sinturel
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Explore the profile of Flore Sinturel including associated specialties, affiliations and a list of published articles.
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23
Citations
492
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Recent Articles
11.
Katsioudi G, Osorio-Forero A, Sinturel F, Hagedorn C, Kreppel F, Schibler U, et al.
Methods Mol Biol
. 2022 May;
2482:217-242.
PMID: 35610430
There is high interest in investigating the daily dynamics of gene expression in mammalian organs, for example, in liver. Such studies help to elucidate how and with what kinetics peripheral...
12.
Sinturel F, Spaleniak W, Dibner C
Biochem Soc Trans
. 2022 May;
50(3):1191-1204.
PMID: 35604112
Lipids comprise a diverse group of metabolites that are indispensable as energy storage molecules, cellular membrane components and mediators of inter- and intra-cellular signaling processes. Lipid homeostasis plays a crucial...
13.
Holtkamp S, Ince L, Barnoud C, Schmitt M, Sinturel F, Pilorz V, et al.
Nat Immunol
. 2021 Oct;
22(11):1375-1381.
PMID: 34663979
Migration of leukocytes from the skin to lymph nodes (LNs) via afferent lymphatic vessels (LVs) is pivotal for adaptive immune responses. Circadian rhythms have emerged as important regulators of leukocyte...
14.
Sinturel F, Gos P, Petrenko V, Hagedorn C, Kreppel F, Storch K, et al.
Genes Dev
. 2021 Feb;
35(5-6):329-334.
PMID: 33602874
It has been assumed that the suprachiasmatic nucleus (SCN) synchronizes peripheral circadian oscillators. However, this has never been convincingly shown, since biochemical time series experiments are not feasible in behaviorally...
15.
Hannich J, Loizides-Mangold U, Sinturel F, Harayama T, Vandereycken B, Saini C, et al.
Acta Physiol (Oxf)
. 2020 Dec;
232(1):e13610.
PMID: 33351229
Aim: The worldwide increase in obesity and type 2 diabetes (T2D) represents a major health challenge. Chronically altered lipids induced by obesity further promote the development of T2D, and the...
16.
Sinturel F, Petrenko V, Dibner C
J Mol Biol
. 2020 Jan;
432(12):3680-3699.
PMID: 31996313
Most organisms adapt to the 24-h cycle of the Earth's rotation by anticipating the time of the day through light-dark cycles. The internal time-keeping system of the circadian clocks has...
17.
Sinturel F, Makhlouf A, Meyer P, Tran C, Pataky Z, Golay A, et al.
Diabetologia
. 2019 May;
62(8):1453-1462.
PMID: 31134308
Aims/hypothesis: The circadian system plays an essential role in regulating the timing of human metabolism. Indeed, circadian misalignment is strongly associated with high rates of metabolic disorders. The properties of...
18.
Sinturel F, Gachon F
Oncotarget
. 2017 Dec;
8(57):96476-96477.
PMID: 29228544
No abstract available.
19.
Sinturel F, Gerber A, Mauvoisin D, Wang J, Gatfield D, Stubblefield J, et al.
Cell
. 2017 May;
169(4):651-663.e14.
PMID: 28475894
The liver plays a pivotal role in metabolism and xenobiotic detoxification, processes that must be particularly efficient when animals are active and feed. A major question is how the liver...
20.
Schibler U, Gotic I, Saini C, Gos P, Curie T, Emmenegger Y, et al.
Cold Spring Harb Symp Quant Biol
. 2015 Dec;
80:223-32.
PMID: 26683231
In mammals, including humans, nearly all physiological processes are subject to daily oscillations that are governed by a circadian timing system with a complex hierarchical structure. The central pacemaker, residing...