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Howard Riezman

Explore the profile of Howard Riezman including associated specialties, affiliations and a list of published articles. Areas
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Articles 147
Citations 6327
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Recent Articles
1.
Sinturel F, Chera S, Brulhart-Meynet M, Montoya J, Lefai E, Jornayvaz F, et al.
iScience . 2024 Sep; 27(9):110820. PMID: 39297163
Besides its beneficial effect on weight loss, gastric bypass surgery (GBS) may impact the circulating levels of phospho- and sphingolipids. However, long-term effects have not been explored. To investigate alterations...
2.
Li X, Tian S, Riezman I, Qin Y, Riezman H, Feng S
J Chromatogr B Analyt Technol Biomed Life Sci . 2024 Aug; 1245:124256. PMID: 39094252
Sphingolipids are a major lipid species found in all eukaryotes. Among structurally complex and diversified lipids, sphingoid bases have been heavily linked to various metabolic diseases. However, most current LC-MS-based...
3.
Girik V, van Ek L, Dentand Quadri I, Azam M, Cruz Cobo M, Mandavit M, et al.
Int J Mol Sci . 2024 Mar; 25(5). PMID: 38474242
Ceramides regulate phagocytosis; however, their exact function remains poorly understood. Here, we sought (1) to develop genetically encoded fluorescent tools for imaging ceramides, and (2) to use them to examine...
4.
Sinturel F, Chera S, Brulhart-Meynet M, Montoya J, Stenvers D, Bisschop P, et al.
Cell Rep Med . 2023 Nov; 4(12):101299. PMID: 38016481
Lipid homeostasis in humans follows a diurnal pattern in muscle and pancreatic islets, altered upon metabolic dysregulation. We employ tandem and liquid-chromatography mass spectrometry to investigate daily regulation of lipid...
5.
Jimenez-Sanchez C, Sinturel F, Mezza T, Loizides-Mangold U, Montoya J, Li L, et al.
Diabetes . 2023 Oct; 73(1):93-107. PMID: 37862465
Article Highlights: Circulating lysophosphatidylinositols (lysoPIs) are increased in situations associated with β-cell loss in mice and humans such as (pre-)diabetes, and hemipancreatectomy. Pancreatic islets isolated from nondiabetic mice and human...
6.
Enkler L, Szentgyorgyi V, Pennauer M, Prescianotto-Baschong C, Riezman I, Wiesyk A, et al.
Nat Cell Biol . 2023 Jul; 25(8):1157-1172. PMID: 37400497
Lipid mobilization through fatty acid β-oxidation is a central process essential for energy production during nutrient shortage. In yeast, this catabolic process starts in the peroxisome from where β-oxidation products...
7.
Petrenko V, Sinturel F, Riezman H, Dibner C
Prog Lipid Res . 2023 May; 91:101235. PMID: 37187314
Lipids play important roles in energy metabolism along with diverse aspects of biological membrane structure, signaling and other functions. Perturbations of lipid metabolism are responsible for the development of various...
8.
Simon C, Asaro A, Feng S, Riezman H
Chem Sci . 2023 Feb; 14(7):1687-1695. PMID: 36819876
Phosphatidylethanolamine metabolism plays essential roles in eukaryotic cells but has not been completely investigated due to its complexity. This is because lipid species, unlike proteins or nucleic acids, cannot be...
9.
Umebayashi M, Takemoto S, Reymond L, Sundukova M, Hovius R, Bucci A, et al.
J Cell Biol . 2022 Dec; 222(3). PMID: 36571579
Functional membrane proteins in the plasma membrane are suggested to have specific membrane environments that play important roles to maintain and regulate their function. However, the local membrane environments of...
10.
Petrenko V, Sinturel F, Loizides-Mangold U, Montoya J, Chera S, Riezman H, et al.
PLoS Biol . 2022 Aug; 20(8):e3001725. PMID: 35921354
Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian...