Fionnuala Morrish
Overview
Explore the profile of Fionnuala Morrish including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
446
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Recent Articles
1.
Morrish F, Gingras H, Noonan J, Huang L, Sweet I, Kuok I, et al.
Biochem Biophys Res Commun
. 2024 Aug;
737:150478.
PMID: 39128225
Genetic polymorphisms in nuclear respiratory factor-1 (Nrf1), a key transcriptional regulator of nuclear-encoded mitochondrial proteins, have been linked to diabetes. Homozygous deletion of Nrf1 is embryonic lethal in mice. Our...
2.
Jaeger-Ruckstuhl C, Lo Y, Fulton E, Waltner O, Shabaneh T, Simon S, et al.
Immunity
. 2024 Feb;
57(2):287-302.e12.
PMID: 38354704
The interaction of the tumor necrosis factor receptor (TNFR) family member CD27 on naive CD8 T (Tn) cells with homotrimeric CD70 on antigen-presenting cells (APCs) is necessary for T cell...
3.
Morrish F, Gingras H, Noonan J, Huang L, Sweet I, Kuok I, et al.
bioRxiv
. 2023 Nov;
PMID: 38014068
Genetic polymorphisms in nuclear respiratory factor-1 ( ), a key transcriptional regulator of nuclear-encoded mitochondrial proteins, have been linked to diabetes. Homozygous deletion of is embryonic lethal in mice. Our...
4.
Tarrago-Celada J, Foguet C, Tarrado-Castellarnau M, Marin S, Hernandez-Alias X, Perarnau J, et al.
Cancers (Basel)
. 2021 Jan;
13(3).
PMID: 33498690
With most cancer-related deaths resulting from metastasis, the development of new therapeutic approaches against metastatic colorectal cancer (mCRC) is essential to increasing patient survival. The metabolic adaptations that support mCRC...
5.
Bluestein B, Morrish F, Graham D, Huang L, Hockenbery D, Gamble L
Biointerphases
. 2018 Aug;
13(6):06D402.
PMID: 30153736
Solid tumors are a structurally complex system, composed of many different cell types. The tumor microenvironment includes nonmalignant cell types that participate in complex interactions with tumor cells. The cross...
6.
Aguilar E, Marin de Mas I, Zodda E, Marin S, Morrish F, Selivanov V, et al.
Stem Cells
. 2016 May;
34(5):1163-76.
PMID: 27146024
In solid tumors, cancer stem cells (CSCs) can arise independently of epithelial-mesenchymal transition (EMT). In spite of recent efforts, the metabolic reprogramming associated with CSC phenotypes uncoupled from EMT is...
7.
Bluestein B, Morrish F, Graham D, Guenthoer J, Hockenbery D, Porter P, et al.
Analyst
. 2016 Feb;
141(6):1947-57.
PMID: 26878076
Imaging time-of-flight secondary ion mass spectrometry (ToF-SIMS) and principal component analysis (PCA) were used to investigate two sets of pre- and post-chemotherapy human breast tumor tissue sections to characterize lipids...
8.
Robinson M, Graham D, Morrish F, Hockenbery D, Gamble L
Biointerphases
. 2015 Aug;
11(2):02A303.
PMID: 26319020
In this work, four triple negative (TN) cell lines, three ER+ and PR+ receptor positive (RP) cell lines, and one ER+, PR+, and HER2+ cell line were chemically distinguished from...
9.
Gamble L, Graham D, Bluestein B, Whitehead N, Hockenbery D, Morrish F, et al.
Biointerphases
. 2015 Feb;
10(1):019008.
PMID: 25708638
The ability to image cells and tissues with chemical and molecular specificity could greatly expand our understanding of biological processes. The subcellular resolution mass spectral imaging capability of time of...
10.
Morrish F, Hockenbery D
Cold Spring Harb Perspect Med
. 2014 May;
4(5).
PMID: 24789872
Mitochondria, the powerhouses of the cell, face two imperatives concerning biogenesis. The first is the requirement for dividing cells to replicate their mitochondrial content by growth of existing mitochondria. The...