Filip Teply
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Explore the profile of Filip Teply including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
137
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Recent Articles
1.
Bilek J, Koval D, Solinova V, Talele H, Severa L, Gutierrez P, et al.
J Sep Sci
. 2024 Jun;
47(11):e2400286.
PMID: 38863086
The enantiomers of diquats (DQs), a new class of functional organic molecules, were recently separated by capillary electrophoresis (CE) with high resolution up to 11.4 within 5-7 min using randomly...
2.
Bilek J, Koval D, Sazelova P, Solinova V, Severa L, Gutierrez P, et al.
J Sep Sci
. 2023 Aug;
46(18):e2300417.
PMID: 37528727
Diquats, derivatives of the widely used herbicide diquat, represent a new class of functional organic molecules. A combination of their special electrochemical properties and axial chirality could potentially result in...
3.
Pavova M, Reyes-Gutierrez P, Kozak J, Dobias J, Yurenko Y, Lepsik M, et al.
Sci Rep
. 2023 Apr;
13(1):6096.
PMID: 37055553
The secondary structure of nucleic acids containing quartets of guanines, termed G-quadruplexes, is known to regulate the transcription of many genes. Several G-quadruplexes can be formed in the HIV-1 long...
4.
Konkolova E, Krejcova K, Eyer L, Hodek J, Zgarbova M, Fortova A, et al.
Molecules
. 2022 Mar;
27(6).
PMID: 35335258
Positive-sense single-stranded RNA (+RNA) viruses have proven to be important pathogens that are able to threaten and deeply damage modern societies, as illustrated by the ongoing COVID-19 pandemic. Therefore, compounds...
5.
Pomeislova A, Vrzal L, Kozak J, Dobias J, Hubalek M, Dvorakova H, et al.
ChemistryOpen
. 2020 Dec;
9(12):1236-1250.
PMID: 33304739
The formation of a G-quadruplex motif in the promoter region of the protooncogene prevents its expression. Accordingly, G-quadruplex stabilization by a suitable ligand may be a viable approach for anticancer...
6.
Reyes-Gutierrez P, Amatov T, Svec P, Cisarova I, Saman D, Pohl R, et al.
Chempluschem
. 2020 May;
85(10):2212-2218.
PMID: 32400944
Helquats (HQs) are structurally linked to helicenes and viologens, and they represent an attractive field of research in chemistry and medicinal chemistry. In the present work they were used as...
7.
Sazelova P, Koval D, Severa L, Teply F, Vigh G, Kasicka V
Electrophoresis
. 2019 Nov;
41(7-8):523-535.
PMID: 31763706
In this study, the apparent binding constants and limiting mobilities of the multiply charged complexes of the Δ- and Λ-enantiomers of Ru(II)- and Fe(II)-polypyridyl associates ([Ru(2,2'-bipyridine) ] , [Ru(1,10-phenanthroline) ]...
8.
Talele H, Koval D, Severa L, Reyes-Gutierrez P, Cisarova I, Sazelova P, et al.
Chemistry
. 2018 Mar;
24(30):7601-7604.
PMID: 29575285
Diquats with extremely high racemization barriers with ΔG of 233 kJ mol at 180 °C are described. Reported configurational robustness is due to a combination of two structural features: the...
9.
Severa L, Sazelova P, Cisarova I, Saman D, Koval D, Devadig P, et al.
Chirality
. 2018 Jan;
30(3):254-260.
PMID: 29293281
Synthesis and nontrivial optical resolution of a helicene-like dication, helquat 1, has been accomplished. Starting with gram scale of the racemic helquat 1 sample, Dutch Resolution using family of 3...
10.
Brandt J, Pospisil L, Bednarova L, da Costa R, White A, Mori T, et al.
Chem Commun (Camb)
. 2017 Jul;
53(65):9059-9062.
PMID: 28737778
Electrochemical reduction of an azoniahelicene affords a dimer, accompanied by a strong change in the electronic circular dichroism. The fast dimerisation event leads to a >500 mV shift of the...