David Saman
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Explore the profile of David Saman including associated specialties, affiliations and a list of published articles.
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65
Citations
268
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Recent Articles
1.
Bildziukevich U, cerna L, Trylcova J, Kvasnicova M, Rarova L, Saman D, et al.
RSC Med Chem
. 2024 Nov;
16(2):801-811.
PMID: 39568596
A series of amides of selected plant triterpenoids, moronic acid and morolic acid, with the tripeptides MAG and GAM, was designed and synthesized. Two required tripeptides 5 and 10 were...
2.
Bildziukevich U, Slouf M, Rarova L, Saman D, Wimmer Z
Soft Matter
. 2023 Sep;
19(39):7625-7634.
PMID: 37772344
Moronic acid and morolic acid, less frequently studied plant triterpenoids, were subjected to derivation with several structural modifiers, namely, piperazine-, pyrazine-, 1-indole- and L-methionine-based compounds. Derivation was targeted to design...
3.
Bildziukevich U, Ozdemir Z, Saman D, Vlk M, Slouf M, Rarova L, et al.
Org Biomol Chem
. 2022 Oct;
20(41):8157-8163.
PMID: 36222062
1,10-Phenanthroline was decorated with triterpenoid-based substituents bearing additional spermine units to form amphiphilic molecules. The synthetic procedure designed for the new phenanthroline-triterpenoid amphiphiles is described in detail. Besides 1,10-phenanthroline, all...
4.
Bildziukevich U, Kvasnicova M, Saman D, Rarova L, Wimmer Z
Plants (Basel)
. 2021 Oct;
10(10).
PMID: 34685891
Background: Oleanolic acid is a natural plant adaptogen, and tryptamine is a natural psychoactive drug. To compare their effects of with the effect of their derivatives, tryptamine and fluorotryptamine amides...
5.
Ozdemir Z, Bildziukevich U, capkova M, Lovecka P, Rarova L, Saman D, et al.
Biomedicines
. 2021 Aug;
9(8).
PMID: 34440155
(1) Background: To compare the effect of selected triterpenoids with their structurally resembling derivatives, designing of the molecular ribbons was targeted to develop compounds with selectivity in their pharmacological effects....
6.
Ozdemir Z, Saman D, Bertula K, Lahtinen M, Bednarova L, Pazderkova M, et al.
Langmuir
. 2021 Feb;
37(8):2693-2706.
PMID: 33595317
Natural and abundant plant triterpenoids are attractive starting materials for the synthesis of conformationally rigid and chiral building blocks for functional soft materials. Here, we report the rational design of...
7.
Ozdemir Z, Rybkova M, Vlk M, Saman D, Rarova L, Wimmer Z
Molecules
. 2020 Aug;
25(15).
PMID: 32756514
The target diosgenin-betulinic acid conjugates are reported to investigate their ability to enhance and modify the pharmacological effects of their components. The detailed synthetic procedure that includes copper(I)-catalyzed Huisgen 1,3-dipolar...
8.
Reyes-Gutierrez P, Amatov T, Svec P, Cisarova I, Saman D, Pohl R, et al.
Chempluschem
. 2020 May;
85(10):2212-2218.
PMID: 32400944
Helquats (HQs) are structurally linked to helicenes and viologens, and they represent an attractive field of research in chemistry and medicinal chemistry. In the present work they were used as...
9.
Bildziukevich U, Malik M, Ozdemir Z, Rarova L, Janovska L, Slouf M, et al.
J Mater Chem B
. 2019 Dec;
8(3):484-491.
PMID: 31834347
Cancer is a global disease of great importance, and the need for novel cytotoxic drugs is still eminent. A series of spermine amides of several selected triterpene acids (betulonic, heterobetulonic,...
10.
Sychrovsky V, Saman D, Fiala R, Humpa O, Sykora J, Kessler P, et al.
Magn Reson Chem
. 2019 Jul;
57(12):1084-1096.
PMID: 31257662
The connectivities of all atoms in ascorbigen A, an important metabolite, were determined unambiguously for the first time. The connectivity between carbon atoms was established by 2D INADEQUATE, and one-bond...