Fernando Lecanda
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Explore the profile of Fernando Lecanda including associated specialties, affiliations and a list of published articles.
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70
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2323
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Recent Articles
1.
Echepare M, Picabea B, Arricibita A, Teijeira A, Pasquier A, Zandueta C, et al.
J Thorac Oncol
. 2024 Nov;
20(3):345-365.
PMID: 39536877
Introduction: Chemotherapy continues to be the standard treatment for patients noneligible for targeted or immune-based therapies; nevertheless, treatment resistance remains a major clinical challenge. We previously found that expression levels...
2.
Macaya I, Roman M, Welch C, Entrialgo-Cadierno R, Salmon M, Santos A, et al.
Nat Commun
. 2023 Oct;
14(1):6332.
PMID: 37816716
Drug combinations are key to circumvent resistance mechanisms compromising response to single anti-cancer targeted therapies. The implementation of combinatorial approaches involving MEK1/2 or KRASG12C inhibitors in the context of KRAS-mutated...
3.
Gianferante D, Moore A, Spector L, Wheeler W, Yang T, Hubbard A, et al.
Cancer Epidemiol
. 2023 Aug;
92():102432.
PMID: 37596165
Introduction: Several studies have linked increased risk of osteosarcoma with tall stature, high birthweight, and early puberty, although evidence is inconsistent. We used genetic risk scores (GRS) based on established...
4.
Entrialgo-Cadierno R, Cueto-Urena C, Welch C, Feliu I, Macaya I, Vera L, et al.
Mol Cancer
. 2023 Jun;
22(1):97.
PMID: 37328838
No abstract available.
5.
Entrialgo-Cadierno R, Cueto-Urena C, Welch C, Feliu I, Macaya I, Vera L, et al.
Mol Cancer
. 2023 May;
22(1):86.
PMID: 37210549
Background: The discovery of functionally relevant KRAS effectors in lung and pancreatic ductal adenocarcinoma (LUAD and PDAC) may yield novel molecular targets or mechanisms amenable to inhibition strategies. Phospholipids availability...
6.
Ruiz-Fernandez de Cordoba B, Martinez-Monge R, Lecanda F
Clin Cancer Res
. 2023 Jan;
29(12):2184-2193.
PMID: 36719675
ENPP1 (ecto-nucleotide pyrophosphatase/phosphodiesterase) participates in the hydrolysis of different purine nucleotides in an array of physiologic processes. However, ENPP1 is frequently overexpressed in local relapses and tumor metastases, which are...
7.
Muley H, Valencia K, Casas J, Moreno B, Botella L, Lecanda F, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674468
Breast cancer (BC) is the most common malignancy in women worldwide. While the main systemic treatment option is anthracycline-containing chemotherapy, chemoresistance continues to be an obstacle to patient survival. Carnitine...
8.
Erice O, Narayanan S, Feliu I, Entrialgo-Cadierno R, Malinova A, Vicentini C, et al.
Clin Cancer Res
. 2023 Jan;
29(6):1137-1154.
PMID: 36607777
Purpose: The identification of pancreatic ductal adenocarcinoma (PDAC) dysregulated genes may unveil novel molecular targets entering inhibitory strategies. Laminins are emerging as potential targets in PDAC given their role as...
9.
Rodriguez-Pena A, Armendariz E, Oyarbide A, Morales X, Ortiz-Espinosa S, Ruiz-Fernandez de Cordoba B, et al.
Bioeng Transl Med
. 2022 Sep;
7(3):e10331.
PMID: 36176621
The analysis of circulating tumor cells (CTCs) in blood is a powerful noninvasive alternative to conventional tumor biopsy. Inertial-based separation is a promising high-throughput, marker-free sorting strategy for the enrichment...
10.
Lasheras-Otero I, Feliu I, Maillo A, Moreno H, Redondo-Munoz M, Aldaz P, et al.
J Invest Dermatol
. 2022 Sep;
143(2):305-316.e5.
PMID: 36058299
Circulating tumor cells are the key link between a primary tumor and distant metastases, but once in the bloodstream, loss of adhesion induces cell death. To identify the mechanisms relevant...