Felix Haberlein
Overview
Explore the profile of Felix Haberlein including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
143
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Recent Articles
1.
Kalanithy J, Mingardo E, Stegmann J, Dhakar R, Dakal T, Rosenfeld J, et al.
J Med Genet
. 2024 Dec;
62(2):126-137.
PMID: 39715634
Background: Previous studies in mouse, and zebrafish embryos show strong expression in progenitor cells of neuronal and neural crest tissues suggesting its involvement in neural crest specification. However, the role...
2.
Haberlein F, Mingardo E, Merten N, Schulze Kohling N, Reinoss P, Simon K, et al.
Cell Chem Biol
. 2022 Sep;
29(10):1541-1555.e7.
PMID: 36126653
Therapies that promote neuroprotection and axonal survival by enhancing myelin regeneration are an unmet need to prevent disability progression in multiple sclerosis. Numerous potentially beneficial compounds have originated from phenotypic...
3.
Wilms C, Lepka K, Haberlein F, Edwards S, Felsberg J, Pudelko L, et al.
Redox Biol
. 2021 Dec;
49:102221.
PMID: 34952462
Redox regulation of specific cysteines via oxidoreductases of the thioredoxin family is increasingly being recognized as an important signaling pathway. Here, we demonstrate that the cytosolic isoform of the vertebrate-specific...
4.
Pfeil E, Brands J, Merten N, Vogtle T, Vescovo M, Rick U, et al.
Mol Cell
. 2020 Nov;
80(6):940-954.e6.
PMID: 33202251
Mechanisms that control mobilization of cytosolic calcium [Ca] are key for regulation of numerous eukaryotic cell functions. One such paradigmatic mechanism involves activation of phospholipase Cβ (PLCβ) enzymes by G...
5.
Bussmann H, Schulte-Michels J, Bingel M, Meurer F, Aatz S, Haberlein F, et al.
Heliyon
. 2020 Jun;
6(5):e03960.
PMID: 32514478
The β-adrenergic receptor (βAR) is relevant for surfactant formation in alveolar type 2 cells and reduction of intracellular calcium concentration in bronchial muscle cells and thus for secretolytic and bronchospasmolytic...
6.
Nagarajan B, Harder A, Japp A, Haberlein F, Mingardo E, Kleinert H, et al.
Glia
. 2019 Nov;
68(3):509-527.
PMID: 31702067
In contrast to humans and other mammals, zebrafish can successfully regenerate and remyelinate central nervous system (CNS) axons following injury. In addition to common myelin proteins found in mammalian myelin,...
7.
Annala S, Feng X, Shridhar N, Eryilmaz F, Patt J, Yang J, et al.
Sci Signal
. 2019 Mar;
12(573).
PMID: 30890659
Somatic gain-of-function mutations of and , which encode α subunits of heterotrimeric Gα proteins, occur in about 85% of cases of uveal melanoma (UM), the most common cancer of the...
8.
Krebs K, Pfeil E, Simon K, Grundmann M, Haberlein F, Bautista-Aguilera O, et al.
ACS Omega
. 2018 Dec;
3(11):14814-14823.
PMID: 30555990
Dynamic mass redistribution (DMR) and cellular dielectric spectroscopy (CDS) are label-free biosensor technologies that capture real-time integrated cellular responses upon exposure to extra- and intracellular stimuli. They register signaling routes...
9.
Schulte-Michels J, Wolf A, Aatz S, Engelhard K, Sieben A, Martinez-Osuna M, et al.
Phytomedicine
. 2016 Feb;
23(1):52-7.
PMID: 26902407
Background: Recently is has been shown that α- and β-hederin increase the β2-adrenergic responsiveness of alveolar type II cells (A549) and human airway smooth muscle cells (HASM), respectively, by inhibiting...
10.
Greunke C, Hage-Hulsmann A, Sorkalla T, Keksel N, Haberlein F, Haberlein H
Pulm Pharmacol Ther
. 2014 Sep;
31:92-8.
PMID: 25234924
The bronchospasmolytic and secretolytic effects of ivy leaves dry extracts can be explained by an increased β2-adrenergic responsiveness of the bronchi. Recently, it was shown that α-hederin inhibits the internalization...