Farideh Ghomashchi
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Explore the profile of Farideh Ghomashchi including associated specialties, affiliations and a list of published articles.
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728
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Recent Articles
1.
Nolin J, Lai Y, Ogden H, Manicone A, Murphy R, An D, et al.
JCI Insight
. 2017 Nov;
2(21).
PMID: 29093264
Phospholipase A2 (PLA2) enzymes regulate the formation of eicosanoids and lysophospholipids that contribute to allergic airway inflammation. Secreted PLA2 group X (sPLA2-X) was recently found to be increased in the...
2.
Liao H, Spacil Z, Ghomashchi F, Escolar M, Kurtzberg J, Orsini J, et al.
Clin Chem
. 2017 Jun;
63(8):1363-1369.
PMID: 28592445
Background: Deficiency of the lysosomal enzyme galactosylcerebrosidase (GALC) causes Krabbe disease. Newborn screening for Krabbe disease is ongoing, but improved methods for follow-up analysis of screen-positive babies are needed to...
3.
Lin N, Huang J, Violante S, Orsini J, Caggana M, Hughes E, et al.
Clin Chem
. 2017 Feb;
63(4):842-851.
PMID: 28196920
Background: Pompe disease (PD) is the first lysosomal storage disorder to be added to the Recommended Uniform Screening Panel for newborn screening. This condition has a broad phenotypic spectrum, ranging...
4.
Kumar A, Masi S, Ghomashchi F, Chennamaneni N, Ito M, Scott C, et al.
Clin Chem
. 2015 Sep;
61(11):1363-71.
PMID: 26369786
Background: There is interest in newborn screening and diagnosis of lysosomal storage diseases because of the development of treatment options that improve clinical outcome. Assays of lysosomal enzymes with high...
5.
Kumar A, Spacil Z, Ghomashchi F, Masi S, Sumida T, Ito M, et al.
Clin Chim Acta
. 2015 Aug;
451(Pt B):125-8.
PMID: 26282597
Background: Treatments have been developed for mucopolysaccharidoses IVA (MPS IVA) and MPS VI suggesting the need for eventual newborn screening. Biochemical enzyme assays are important for diagnosis. Previously reported fluorimetric...
6.
Berry E, Hernandez-Anzaldo S, Ghomashchi F, Lehner R, Murakami M, Gelb M, et al.
J Am Heart Assoc
. 2015 Mar;
4(4).
PMID: 25820137
Background: Matrix metalloproteinase (MMP)-2 deficiency makes humans and mice susceptible to inflammation. Here, we reveal an MMP-2-mediated mechanism that modulates the inflammatory response via secretory phospholipase A2 (sPLA2), a phospholipid...
7.
Ghomashchi F, Barcenas M, Turecek F, Scott C, Gelb M
Clin Chem
. 2015 Mar;
61(5):771-2.
PMID: 25770139
No abstract available.
8.
Wolfe B, Ghomashchi F, Kim T, Abam C, Sadilek M, Jack R, et al.
Bioconjug Chem
. 2012 Mar;
23(3):557-64.
PMID: 22372747
The clinical phenotype of Sanfilippo Syndrome is caused by one of four enzyme deficiencies that are associated with a defect in mucopolysaccharide metabolism. The four subtypes (A, B, C, and...
9.
Reed K, Tucker D, Aloulou A, Adler D, Ghomashchi F, Gelb M, et al.
Biochemistry
. 2011 Jan;
50(10):1731-8.
PMID: 21247147
Group IVA cytosolic phospholipase A(2) (cPLA(2)α) catalyzes the first step in the arachidonic acid cascade leading to the synthesis of important lipid mediators, the prostaglandins and leukotrienes. We previously described...
10.
Ghomashchi F, Naika G, Bollinger J, Aloulou A, Lehr M, Leslie C, et al.
J Biol Chem
. 2010 Aug;
285(46):36100-11.
PMID: 20705608
The cytosolic (group IV) phospholipase A(2) (cPLA(2)s) family contains six members. We have prepared recombinant proteins for human α, mouse β, human γ, human δ, human ε, and mouse ζ...